Table 3 Comparison of COVID-positive inpatients during predominantly-Omicron period (December 2021–January 2022) by vaccination status
Not vaccinated | Under-vaccinated | Fully vaccinated w/o booster | Fully vaccinated with booster | P* | |
|---|---|---|---|---|---|
N | 572 | 49 | 266 | 70 | |
Age, years | 56.8 ± 19.9 | 53.3 ± 17.6 | 62.1 ± 19.4 | 66.8 ± 18.8 | < 0.0001 |
Male sex | 280 (49.0%) | 24 (49.0%) | 140 (52.6%) | 42 (60.0%) | 0.31 |
Morbid obesity (BMI > 40) | 53 (9.7%) | 4 (8.3%) | 21 (8.1%) | 4 (6.0%) | 0.71 |
Charlson’s comorbidity index (CCI) | 3.84 ± 3.53 | 5.16 ± 3.82 | 6.14 ± 4.41 | 6.77 ± 3.77 | < 0.0001 |
Elixhauser’s comorbidity index (ECI) | 11.5 ± 12.1 | 15.0 ± 13.2 | 17.0 ± 14.6 | 18.5 ± 13.0 | < 0.0001 |
O2 saturation at admission ≤ 90% | 133 (23.3%) | 8 (16.3%) | 34 (12.8%) | 9 (13.0%) | 0.0016 |
COVID-19 pneumonia | 402 (70.3%) | 22 (44.9%) | 153 (57.5%) | 35 (50.0%) | < 0.0001 |
Coagulopathy | 72 (12.6%) | 5 (10.2%) | 34 (12.8%) | 12 (17.1%) | 0.68 |
LOS, days | 7.79 ± 7.29 | 6.71 ± 5.12 | 6.71 ± 5.75 | 6.74 ± 5.32 | 0.22 |
Admitted to ICU | 84 (14.7%) | 6 (12.2%) | 41 (15.4%) | 12 (17.1%) | 0.89 |
LOS in ICU, days | 5.91 ± 7.35 | 5.29 ± 4.53 | 4.24 ± 4.83 | 5.13 ± 8.12 | 0.53 |
Mechanical ventilation | 41 (7.2%) | 3 (6.1%) | 18 (6.8%) | 7 (10.0%) | 0.81 |
Disposition: short-term care facility | 2 (0.3%) | 0 (0.0%) | 2 (0.8%) | 2 (2.9%) | 0.08 |
Disposition: long-term care facility | 43 (7.5%) | 4 (8.2%) | 22 (8.3%) | 11 (15.7%) | 0.14 |
Disposition: home | 468 (81.8%) | 40 (81.6%) | 208 (78.2%) | 46 (65.7%) | 0.0148 |
Disposition: hospice | 23 (4.0%) | 1 (2.0%) | 10 (3.8%) | 3 (4.3%) | 0.91 |
Expired | 36 (6.3%) | 4 (8.2%) | 24 (9.0%) | 8 (11.4%) | 0.30 |