BMC Infectious Diseases

Table 2 hrHPV DNA, p16^(INK4a) (p16) and combined hrHPV DNA/p16^(INK4a) test results by hrHPV RNA status in cancers of the oropharynx, tonsils and base of the tongue

From: Accuracy of high-risk HPV DNA PCR, p16^(INK4a) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer

		hrHPV RNA
		Pos	Neg
		N	N	Total
hrHPV DNA
Oropharynx	Pos	28	5	33
	Neg	0	62	62
	Total	28	67	95
Tonsil	Pos	19	3	22
	Neg	0	20	20
	Total	19	23	42
Base of tongue	Pos	7	0	7
	Neg	0	14	14
	Total	7	14	21
p16
Oropharynx	Pos	27	5	32
	Neg	1	62	63
	Total	28	67	95
Tonsil	Pos	18	2	20
	Neg	1	21	22
	Total	19	23	42
Base of tongue	Pos	7	2	9
	Neg	0	12	12
	Total	7	14	21
p16 + DNA
Oropharynx	Pos	27	2	29
	Neg	1	65	66
	Total	28	67	95
Tonsil	Pos	18	2	20
	Neg	1	21	22
	Total	19	23	42
Base of tongue	Pos	7	0	7
	Neg	0	14	14
	Total	7	14	21
p16 → DNA
Oropharynx	Pos	27	2	29
	Neg	1	65	66
	Total	28	67	95
Tonsil	Pos	18	2	20
	Neg	1	21	22
	Total	19	23	42
Base of tongue	Pos	7	0	7
	Neg	0	14	14
	Total	7	14	21
DNA → p16
Oropharynx	Pos	27	2	29
	Neg	1	65	66
	Total	28	67	95
Tonsil	Pos	18	2	20
	Neg	1	21	22
	Total	19	23	42
Base of tongue	Pos	7	0	7
	Neg	0	14	14
	Total	7	14	21

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ISSN: 1471-2334

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