Table 1 Prevalence of HPV determined by HPV DNA PCR (DNA), p16(INK4a) IHC (p16), E6*I mRNA (RNA), and all combinations of tests, in oropharyngeal cancer
Marker positivity | Oropharyngeal cancer | |||
|---|---|---|---|---|
Positive | Proportion | (95% CI) | ||
DNA | (N = 99) | 36a | 36.4% | (27.4–46.4) |
p16 | (N = 97)b | 33 | 34.0% | (25.2–44.1) |
RNA | (N = 97)c | 28 | 28.9% | (20.6–38.8) |
p16 + DNA | (N = 97) | 30 | 30.9% | (22.5–40.9) |
DNA + RNA | (N = 97) | 28 | 28.9% | (20.6–38.8) |
RNA + p16 | (N = 95) | 27 | 28.4% | (20.2–38.4) |
p16 + DNA + RNA | (N = 95) | 27 | 28.4% | (20.2–38.4) |