Table 1 Relative changes in the yearly incidence rates of hepatitis A in different regions in mainland China from 2004 to 2017 based on joinpoint regression analysis

2004–2007

0.1 (− 9.5 to 10.7)

0.984

 − 10.6 (− 14.3– − 6.8)*

 < 0.001

2007–2012

 − 19.7 (− 26.2– − 12.7)*

0.001

2012–2017

 − 7.0 (− 14.9–1.6)

0.090

2004–2017

 − 15.0 (− 16.8– − 13.2)*

 < 0.001

 − 15.0(− 16.8– − 13.2)*

 < 0.001

2004–2011

 − 20.7 (− 27.0– − 14.0)*

 < 0.001

 − 6.2(− 12.5–0.5)

0.070

2011–2017

14.2 (− 1.2–31.9)

0.068

2004–2012

 − 16.7 (− 19.0– − 14.4)*

 < 0.001

 − 10.5(− 13.2– − 7.7)*

 < 0.001

2012–2017

0.5 (− 7.4–9.1)

0.891