Skip to main content

Table 2 Distribution of laboratory results according to CRP levels

From: Could combined rapid diagnostic testing for malaria and c-reactive protein be helpful for the diagnosis and management of febrile illnesses in children under-5 years of age in rural Burkina Faso?

Laboratory findings

Negative CRP level

Positive CRP level

 < 10 mg/L

10–40 mg/L

 > 40 mg/L

Malaria RDT PfHRP2 (N = 396), n (%)

62 (15.7)

65 (16.4)

269 (67.9)

 Positive (n = 272), n (%)

18 (6.6)

33 (12.1)

221 (81.3)

 Negative (n = 124), n (%)

44 (35.5)

32 (25.8)

48 (38.7)

Bacterial infections (n = 49), n (%)

7 (14.3)

6 (12.2)

36 (73.5)

 bBSI (n = 23), n (%)

1 (4.3)

3 (13.1)

19 (82.6)

 bGE (n = 25), n (%)

5 (20)

3 (12.0)

17 (68.0)

 bUTI (n = 1), n (%)

1 (100)

0 (0.0)

0 (0.0)

Non-bacterial infections (n = 74), n (%)

11 (14.9)

14 (18.9)

49 (66.2)

 pGE (n = 70), n (%)

10 (14.3)

13 (18.6)

47 (67.1)

 vGE (n = 4), n (%)

1 (25.0)

1 (25.0)

2 (50.0)

Children with one or more infection(s) (n = 311), n (%)

30 (9.6)

41 (13.2)

240 (77.2)

 Malaria alone (as determined by RDT) (n = 196), n (%)

14 (7.1)

22 (11.2)

160 (81.6)

 pGEs alone (n = 16), n (%)

6 (37.5)

3 (18.75)

7 (43.75)

 bBSIs alone (n = 11), n (%)

1 (9.1)

3 (27.3)

7 (63.6)

 bGEs alone (n = 6), n (%)

3 (50.0)

1 (16.7)

2 (33.3)

 vGEs alone (n = 3), n (%)

0 (0.0)

1 (33.3)

2 (66.7)

 Malaria combined with either a bacterial or a parasitic infection (n = 76), n (%)

4 (5.3)

11 (14.7)

61 (80.3)

 No malaria infection but either a bacterial infection combined with a parasitic infection (n = 2) or a combination of a viral infection with a bacterial infection (n = 1), n (%)

2 (66.7)

0 (0.0)

1 (33.3)

Children with unknown cause of fevera (n = 81), n (%)

30 (37.0)

23 (28.4)

28 (34.6)

  1. CRP: C-reactive protein; RDT-PfHRP2: rapid diagnostic test for Plasmodium falciparum-specific histidine-rich protein 2; bBSI: bacterial bloodstream infection; bGE: bacterial gastroenteritis; bUTI: bacterial urinary tract infection; pGE: parasitic gastroenteritis; vGE: viral gastroenteritis
  2. aChildren having negative malaria testing (RDT-PfHRP2 and microscopy) and negative microbiology analyses (Bacterial infections and non-bacterial infections)