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Table 3 Analysis of the primary and the secondary outcomes

From: Health care consequences of hospitalization with Clostrioides difficile infection: a propensity score matching study

Outcome

Incidence CDI cases

Control

Diff (95% CI)

p-value*

OR(95% CI)**

30 d Readmission (n = 

28,846 pairs)

28.26%

19.46%

8.81 (8.11–9.5)

< 0.0001

1.63 (95% CI 1.57–1.70)

60 d Readmission (n = 28,846 pairs)

37.65%

26.02%

11.62 (10.87–12.38)

< 0.0001

1.71(95% CI 1.65–1.77)

90 d Readmission (n = 28,846 pairs)

42.93%

30.43%

12.5 (11.72–13.28)

< 0.0001

1.71(95% CI 1.66–1.77)

120 d Readmission (n = 28,846 pairs)

46.47%

33.74%

12.73 (11.94–13.52)

< 0.0001

1.70 (95% CI 1.64–1.76)

180 d Readmission (n = 28,846 pairs)

51.39%

38.76%

12.63 (11.82–13.43)

< 0.0001

1.66 (95% CI 1.61–1.72)

Mortality within 7 days of discharge (n = 28,874 pairs)

3.68%

2.01%

1.67 (1.4–1.94)

< 0.0001

1.86 (95% CI 1.68–2.07)

Mortality within 15 days of discharge (n = 28,874 pairs)

5.76%

3.17%

2.59 (2.26–2.93)

< 0.0001

1.87 (95% CI 1.72–2.03)

Mortality within 30 days of discharge (n = 28,874 pairs)

8.65%

4.71%

3.93 (3.53–4.34)

< 0.0001

1.90 (95% CI 1.78–2.03)

Mortality within 180 days of discharge

(n = 28,874 pairs)

20.54%

11.96%

8.58 (7.98–9.17)

< 0.0001

1.88 (95% CI 1.80–1.97)

Mortality within 360 days of discharge

(n = 28,874 pairs)

26.15%

16.55%

9.6 (8.93–10.26)

< 0.0001

1.75 (95% CI 1.69–1.82)

LOS in days-Median (25-75th Perc.) (n = 28,874 pairs)

9 (5–16)

4 (2–7)

4 (0–11)

< 0.0001

 

Total Charges ($)- Geometric mean (95% CI) (n = 28,874 pairs)

58,430 (57,689 − 59,181)

31,705 (31,363 − 32,051)

Percentage increase of total charges for CDI relative to control: 84% (81–87%)

< 0.0001

 
  1. *p-values were based on the McNemar’s test (Mortality and the Readmission indicators), the paired t-test (Log(Total Charges)) and the Wilcoxon signed rank test (LOS)
  2. **p-values based on a generalized linear mixed model with a random effect for hospital and a random effect for the matched pair