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Table 2 Safety of convalescent plasma in the per-protocol analysis

From: Safety and efficacy of convalescent plasma for severe COVID-19: a randomized, single blinded, parallel, controlled clinical study

Adverse events

Standard therapy (n = 45)

Plasma recipients (n = 46)

OR (95% CI)

Overall

14 (31.1%)

13 (28.3%)

0.87 (0.32 to 2.36)

Serious

13 (28.9%)

11 (23.9%)

0.78 (0.27 to 2.18)

MV

10 (22.2%)

7 (15.2%)

–

ICU admission

0 (0.0%)

2 (4.4%)

–

Pulmonary embolism

1 (2.2%)

1 (2.2%)

–

DVT

0 (0.0%)

1 (2.2%)

–

Pneumatocele

1 (2.2%)

0 (0.0%)

–

Readmission

1 (2.2%)

0 (0.0%)

–

Non-seriousa

1 (2.2%)

2 (4.4%)

2.0 (0.10 to 120.54)

Rash with pruritus

1 (2.2%)

1 (2.2%)

–

Palpebral edema

0 (0.0%)

1 (2.2%)

–

  1. a A patient presented rash with pruritus and palpebral edema after administration of CP (related adverse event). CP: Convalescent plasma; DVT: Deep venous thrombosis; ICU: Intensive care unit; MV: Mechanical ventilation; OR: Odds ratio; CI: Confidence interval