Fig. 4From: Safety and efficacy of convalescent plasma for severe COVID-19: a randomized, single blinded, parallel, controlled clinical studyComparative genomics and nucleotide diversity analyses among SARS-CoV-2 genomes obtained in this study. A Phylogenomic relationships using a maximum likelihood phylogeny obtained in Nextclade. B Whole-genome substitutions profiles for the eleven genomes from five patients with more than one sample. Mismatches were identified by comparison with the Wuhan reference sequence (NC_045512.2). The substitutions shared among each group of samples are represented in grey and the substitutions found on any of the sample's days are represented in Red (non-synonymous substitutions) or light green (SS: synonymous substitutions). Inside of each green box is described the type of substitutionsBack to article page