Table 1 Inclusion criteria and exclusion criteria

Inclusion criteria:

1. 18 years old or older

2. Meet at least two of SIRS^a criteria:

➀ Temperature > 38 ℃ or < 36 ℃

➁ Heart rate > 90 bpm

➂ Respiratory rate > 20 or PaCO₂ < 32 mmHg

➃ WBC > 12,000/µL or < 4000/µL or > 10% bands

3. Hospitalized patients who have a diagnostic blood culture drawn on the same

day as enrollment (day 0), which is the standard procedure for suspected sepsis

4. Written informed consent signed by the patient or their legal representative

Exclusion criteria:

1. Refusal to participate in the study or failure to comply with treatment or follow-up

2. Known pregnancy or lactation

3. The researcher believes that there are any conditions (social or medical) that allow subjects to participate is unsafe. For example, severe anemia or high risk of bleeding, etc., which are not suitable for taking peripheral blood for testing

4. Participating in other clinical studies