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Table 4 The vacA s1m1-positive status and metronidazole resistance

From: Clinical relevance of the cagA and vacA s1m1 status and antibiotic resistance in Helicobacter pylori: a systematic review and meta-analysis

Factors

Random-effects model

Heterogeneity

OR

95%CI

p value

p value

I-squared

Level of country

Developing country

0.30

0.13–0.68

0.01

0.01

86.26

Developed country

0.55

0.18–1.65

0.01

0.01

93.33

Sample size

≥ 100

1.13

0.84–1.52

0.01

0.31

24.65

≤ 100

0.28

0.13–0.60

0.01

0.05

64.32

Diagnostic test

E-test

0.64

0.26–1.57

0.3

0.02

58.32

Agar dilution based

0.25

0.03–1.79

0.17

0.5

32.81

Disk diffusion based

2.12

0.96–4.67

0.05

0.9

0.00

Molecular based

1.33

0.46–3.80

0.03

0.9

0.00