Author | Year | Country | Gestational age (weeks) | Clinical presentation | Suspected risk factors | Confirmed investigations | Treatment | Pregnancy outcome |
---|---|---|---|---|---|---|---|---|
Waites et al. [29] | 1984 | The United States | 16 | Intrauterine fetal death | Retained copper IUD | Positive culture from amniotic fluid No evidence of positive culture of S. mitis from vaginal swab, placenta, or fetus | Post-abortion antibiotics (Metronidazole + doxycycline) | Asymptomatic intrauterine infection with intrauterine fetal death |
Schmiedel et al. [27] | 2014 | Germany | 30 | Sudden onset of maternal fever and fetal tachycardia | None | Positive culture from intraoperative swabs from placenta and fetal membranes with routine culture methods and visualized on FISH analysis Vaginal swabs with routine method was negative for S. Mitis | Cefuroxime | Acute chorioamnionitis was diagnosed and Cesarean delivery was performed at 30 weeks’ gestation |
Hosseini, Hunt [28] | 2020 | Canada | 21 | Preterm labor (cervix dilated 4–5 cm) with afebrile with no evidence of any infectious symptoms | Recent dental scaling and recent cunnilingus with a partner known to have periodontal disease | S. mitis was isolated from a culture of amniotic membrane Placental pathology showed signs of acute chorioamnionitis including acute inflammation of placental plate chorion and acute funisitis |  | Delivered a male infant weight 510 g consistent with gestational age of approximately 22 weeks and died 1 h after delivery |