Fig. 2

Monocyte anisocytosis is associated with MIS-C. A Discovery Cohort: Monocyte Distribution Width (MDW, a measure of monocyte anisocytosis) was quantified in blood samples from children with MIS-C, other infectious or inflammatory illnesses, and healthy controls. Analysis by ordinary one-way ANOVA. ****P < 0.0001. B Receiver operator curve (ROC) was used to assess the ability of MDW to serve as a tier 1 assay for distinguishing children with MIS-C from other children. An MDW threshold of 24 was established and tested in this discovery cohort for the ability to distinguish MIS-C from other illnesses. AUC = area under the curve (percentage). Single outlier identified by Grubb’s outlier test in the infection-inflammation group was removed for this analysis