Variables | Unadjusted model HR (95% CI) | p-value | Adjusted model HR (95% CI) | p-value |
---|---|---|---|---|
Age | ||||
10 year increase | 1.34 (1.16–1.56) | < 0.0001 | 1.25 (1.05–1.47) | 0.01 |
Ethnicity/skin color | ||||
White | 1.00 | – | 1.00 | – |
Black | 1.41 (0.90–2.21) | 0.14 | 0.97 (0.61–1.54) | 0.88 |
Brown | 1.28 (0.85–1.92) | 0.24 | 1.06 (0.71–1.59) | 0.78 |
Years of education | ||||
≤ 5 | 2.55 (1.72–3.78) | < 0.0001 | 1.56 (1.02–2.39) | 0.04 |
6–9 | 1.82 (1.08–3.07) | 0.02 | 1.30 (0.77–2.21) | 0.33 |
≥ 10 | 1.00 | – | 1.00 | – |
Year of first visit | ||||
2004–2006 | 0.97 (0.58–1.63) | 0.92 | – | – |
2007–2009 | 0.93 (0.57–1.51) | 0.77 | – | – |
2010–2012 | 1.07 (0.67–1.70) | 0.79 | – | – |
2013–2015 | 1.00 | – | – | – |
Gender/sexual preference | ||||
Cis-W | 1.00 | – | 1.00 | – |
Trans-W | 0.44 (0.10–1.82) | 0.25 | 0.84 (0.20–3.58) | 0.82 |
MSM | 1.19 (0.71–1.99) | 0.50 | 1.43 (0.84–2.45) | 0.18 |
MSW | 1.87 (1.11–3.14) | 0.02 | 1.14 (0.69–1.88) | 0.61 |
ART-naïve before first visit | ||||
No | 1.00 | – | 1.00 | – |
Yes | 2.89 (1.60–5.23) | < 0.001 | 2.52 (1.37–4.62) | < 0.01 |
CD4 count (cells/µL) | ||||
≤ 50 | 39.92 (14.45–110.27) | < 0.0001 | 9.98 (3.32–29.94) | < 0.0001 |
51–200 | 22.85 (9.03–57.85) | < 0.0001 | 8.05 (2.98–21.77) | < 0.0001 |
201–350 | 3.05 (0.69–13.39) | 0.14 | 1.90 (0.42–8.50) | 0.40 |
> 350 | 1.00 | – | – | – |
Viral load | ||||
< 400 | 1.00 | – | 1.00 | – |
400 a 999 | 1.77 (0.41–7.54) | 0.33 | 2.47 (0.64–9.59) | 0.19 |
≥ 1000 | 2.01 (1.08–3.72) | 0.03 | 1.23 (0.65–2.33) | 0.52 |
Prior AIDS defining illness | ||||
No | 1.00 | – | 1.00 | – |
Yes | 19.27 (11.72–31.67) | < 0.0001 | 7.13 (4.11–12.37) | < 0.0001 |