Clinical analysis on diagnostic accuracy of Bosch Vivalytic SARS-CoV-2 point-of-care test and evaluation of cycle threshold at admission for COVID-19 risk assessment

Table 5 Baseline characteristics at admission in patients hospitalized with COVID-19 disease with length of hospital stay (LOS) above or below 10 days respectively

Variable	LOS < 10 days n = 23		LOS ≥ 10 days n = 23		P-value
LOS*	4.7	(± 2.7)	21	(± 17)
Age (years)	45.6	(± 14)	62.4	(± 62.4)	0.001^b
Sex (female)	7	(30.4%)	8	(34.8%)	0.753^c
C-reactive protein (mg/dl)	3.6	(0.4–7.6)	7.7	(± 6.3)	0.051^b
Haemoglobine (g/dl)	13.6	(± 1.7)	11.9	(± 2.3)	0.007^b
Leukocytes (Tsd/ul)	7.5	(± 4)	7.4	(4.9–10)	0.628^a
Platlets (Tsd/ul)	209	(173–257)	233	(181—282)	0.652^a
Lactate dehydrogenase (U/I)	330	(258–469)	377	(230–447)	0.989^a
Aspartate Aminotransferase (U/I)	38	(16–38)	46	(± 30)	0.941^a
CAD**	2	(9%)	6	(25%)	0.119^c
Hypertension	7	(29%)	11	(48%)	0.567^c
Pulmonary disease	4	(17%)	5	(22%)	0.710^c
Virus Variant B1.1.7	15	(65%)	11	(48%)	0.234^c
POC-CT*** at admission	36.2	(25.9–39.18)	27.82	(± 4.648)	0.019^a
Vital parameters at admission
Mean Pressure (mmHg)	94.5	(81–105)	90	(87–94)	0.616^a
Temperature	37.6	(36.8–38.5)	37.4	(36.5–38.1)	0.410^a
Respiratory Rate (per min.)	18.3	(± 4.8)	17.6	(± 3.2)	0.530^b
Heart Rate (Beats/minute)	87.7	(± 15.1)	92.4	(± 18.7)	0.367^b
Saturation at admission (%)	96	(94.8–98)	95.5	(89.5–96.3)	0.127^a

*LOS = Length of stay; **CAD_ Coronary Artery Disease; ***CT = Cycle Threshold only CT values of the Point-of Care test (LOS < 10 days n = 20 and LOS ≥ 10 days n = 20); Continuous variables are presented as mean ± standard deviation (SD) if found to follow a Gaussian distribution according to the D’Agosstino-Pearson omnibus normality test or as median ± lower and upper quartiles if found to follow a non-Gaussian distribution. ^anonparametric Mann–Whitney U test to compare ranks; ^bunpaired t-test; ^cFisher’s exact test

ISSN: 1471-2334