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Table 1 Bivariate and multivariable analysis of CRAB cultures evaluating association between patient/facility characteristics and 90-day mortality

From: Epidemiology and outcomes associated with carbapenem-resistant Acinetobacter baumannii and carbapenem-resistant Pseudomonas aeruginosa: a retrospective cohort study

Characteristics
[N = 1048]
Death 90 days after culture date (%) [N = 318] No death 90 days after culture date (%) [N = 730] Unadjusted odds ratio
(95% CI)
Adjusted odds ratio
(95% CI)
Demographic and clinical characteristics     
 Male 315 (99.1) 709 (97.1) 3.11 (0.92–10.5)
Age category     
 18–49 3 (0.9) 50 (6.9) Reference Reference
 50–64 61 (19.2) 258 (35.3) 3.92 (1.19–13.05) 3.24 (0.93–11.34)
 65 +  254 (79.9) 422 (57.8) 10.03 (3.10–32.5) 7.41 (2.16–25.37)
Race     
 White 200 (62.9) 455 (62.3) Reference
 African American 112 (35.1) 263 (36.0) 0.97 (0.74–1.28)
 Other* 6 (1.9) 12 (1.6) 1.14 (0.42–3.07)
Ethnicity     
 Non-Latine 260 (81.8) 673 (92.2) Reference
 Latine 58 (18.2) 57 (7.8) 2.63 (1.78–3.90)
Region     
 South 139 (43.7) 375 (51.4) Reference Reference
 Midwest 40 (12.6) 133 (18.2) 0.81 (0.54–1.22) 0.77 (0.49–1.21)
 West 65 (20.4) 111 (15.2) 1.58 (1.10–2.27) 1.21 (0.81–1.82)
 Northeast 22 (6.9) 71 (9.7) 0.84 (0.50–2.40) 0.59 (0.34–1.05)
 U.S. Territory 52 (16.4) 40 (5.5) 3.51 (2.22–5.53) 2.03 (1.19–3.45)
Rurality     
 Urban 308 (96.9) 697 (95.5) Reference
 Rural 10 (3.1) 33 (4.5) 0.69 (0.33–1.41)
Facility complexity     
 High 315 (99.1) 710 (97.3) Reference
 Low 3 (0.9) 20 (2.7) 0.34 (0.10–1.15)
Care setting     
 Outpatient 61 (19.2) 202 (27.7) Reference Reference
 Long-term care 26 (8.2) 201 (27.5) 0.43 (0.26–0.71) 0.30 (0.16–0.54)
 Inpatient 231 (72.6) 327 (44.8) 2.34 (1.68–3.26) 1.59 (1.09–2.32)
Specimen type     
 Urine 50 (15.7) 257 (25.2) Reference Reference
 Respiratory 124 (39.0) 127 (17.4) 5.02 (3.39–7.42) 3.84 (2.48–5.93)
 Blood 36 (11.3) 20 (2.7) 9.25 (4.95–17.28) 6.98 (3.55–13.73)
 Other 108 (34.0) 326 (44.7) 1.70 (1.17–2.47) 1.68 (1.12–2.52)
Co-morbidities     
 Mean Charlson Score (SD) 6 (3.2) 5 (2.8)  < 0.0001§ 1.11 (1.05–1.17)
 SCI/D     
  No 272 (85.5) 482 (66.0) Reference
  Yes 46 (14.5) 248 (34.0) 0.33 (0.23–0.47)
Antibiotic exposure in previous 90 days     
 Any antibiotics    
  No 230 (72.3) 462 (63.3) Reference Reference
  Yes 88 (27.7) 268 (36.7) 0.66 (0.50–0.88) 0.65 (0.46–0.91)
 Fluoroquinolones     
  No 274 (86.2) 593 (81.2) Reference
  Yes 44 (13.8) 137 (18.8) 0.70 (0.48–1.01)
 3rd and 4th generation cephalosporins     
  No 311 (97.8) 712 (97.5) Reference
  Yes 7 (2.2) 18 (2.5) 0.89 (0.37–2.15)
 Carbapenems     
  No 316 (99.4) 725 (99.3) Reference
  Yes 2 (0.6) 5 (0.7) 0.92 (0.18–4.76)
 Length of stay 1 year prior to culture     
  Mean, median (SD) 75, 25 (95.5) 67, 31 (89.7) 0.1831§ 1.00 (1.00–1.00)
  1. Significant associations are shown in bold (p < 0.05)
  2. *Other includes, Asian, Native American and Pacific Islander
  3. Other specimen types include wounds, skin/soft tissue, body fluid, bone/joint, rectal cultures
  4. Respiratory specimen types include bronchial alveolar, tracheal aspirate, induced sputum, etc.
  5. §T-test p-value