Table 1 Baseline characteristics of the study participants
Characteristic | Normal-25(OH)D group (n = 35) | 25(OH)D < 75 nmol/L | P | |
|---|---|---|---|---|
Low-25(OH)D group (n = 35) | Low-25(OH)D-Calcitriol group (n = 35) | |||
Age (years) | 43.3 ± 14.0 | 56.1 ± 14.0* | 56.7 ± 14.0* | < 0.05 |
Sex | 0.986 | |||
 Male | 20 (57.1%) | 21 (60.0%) | 22 (62.8%) |  |
 Female | 15 (42.9%) | 14 (40.0%) | 13 (37.2%) |  |
Body mass index (BMI) (kg/m2) | 21.0 ± 1.4 | 19.8 ± 1.2 | 19.7 ± 1.2 | 0.955 |
Smoker | 25 (71.4%) | 26 (74.3%) | 26 (74.3%) | 0.988 |
Alcohol consumption | 26 (74.3%) | 27 (77.1%) | 26 (74.3%) | 0.987 |
Sputum smear at enrollment (n = 35/group) |  | |||
 Positive | 35 (100%) | 35 (100%) | 35 (100%) |  |
 Negative | – | – | – |  |
Tuberculosis score | 3.37 ± 1.14 | 3.42 ± 1.15 | 3.41 ± 1.15 | 0.971 |
Serum 25(OH)D level (nmol/L) | 79.3 ± 3.4 | 37.8 ± 13.4* | 39.3 ± 11.9* | < 0.05 |
White blood cell count (×109/L) | 6.2 ± 1.4 | 5.5 ± 1.1 | 5.4 ± 1.0 | 0.933 |
Hemoglobin (g/L) | 109 ± 12 | 104 ± 10 | 105 ± 11 | 0.901 |
CD4+ T cell count (cells/µL) | 671.1 ± 286.9 | 199.7 ± 110.2* | 193.9 ± 119.2* | < 0.05 |
Chest radiography | 0.289 | |||
 Cavities present | 16 (45.7%) | 17 (42.9%) | 16 (45.7%) |  |
 Cavities absent | 19 (54.3%) | 18 (57.1%) | 19 (54.3%) |  |
Drug sensitivity profile | Â | |||
 Multidrug-resistant | 35 (100%) | 35 (100%) | 35 (100%) |  |
 Non-multidrug-resistant | 0 (0%) | 0 (0%) | 0 (0%) |  |
Treatment regimen | Â | 0.964 | ||
 2HRZE/4HR | 25 (71.4%) | 24 (68.6%) | 23 (65.7%) |  |
 2HRtLE/4HRt | 10 (28.6%) | 11 (31.4%) | 12 (34.3%) |  |