Evolution and spread of a highly drug resistant strain of Mycobacterium tuberculosis in Papua New Guinea

BMC Infectious Diseases

Table 2 Genotypic susceptibility of Mycobacterium tuberculosis strains in NCD, Daru, and other PNG provinces

WHO Group	Anti-TB drug	% NCD strains susceptible (n = 66)	% Daru strains susceptible (n = 100)	% Other province strains susceptible (n = 28)
Group A	Levofloxacin OR moxifloxacin	95	88	96
	Bedaquiline	98	100	100
	Linezolid	100	100	100
Group B	Clofazimine	98	100	100
Group B	Cycloserine OR terizidone	100	100	100
Group C	Ethambutol	52*	44*	71*
	Delamanid	100	100	100
	Pyrazinamide	61*	43*	75*
	Imipenem-cilastatin OR meropenem, with clavulanic acid	Unknown
	Amikacin	98	98	100
	Streptomycin	36	12	42
	Ethionamide OR prothionamide	38*	14*	46*
	Para-aminosalicylic acid	98	100	98
–	High dose Isoniazid	27*	33*	29*

NCD National Capital District, PNG Papua New Guinea, TB Tuberculosis
^*Concern about decreased susceptibility to TB drugs included in the WHO approved all-oral short course RR/MDR-TB drug regimen

ISSN: 1471-2334