Impact of antimicrobial stewardship programs on antibiotic consumption and antimicrobial resistance in four Colombian healthcare institutions

Table 4 Incidence of MEM-R Aba, CRO-R Eco, ETP-R Kpn, MEM-R Pae, and OXA-R Sau per 1000 patient admissions in Colombian healthcare institutions pre- and post-intervention

Value	MEM-R Aba		MEM-R Pae		CRO-R Eco		ETP-R Kpn		OXA-R Sau
Value	Coefficient (95% CI)	p	Coefficient (95% CI)	p	Coefficient (95% CI)	p	Coefficient (95% CI)	p	Coefficient (95% CI)	p
β₀	6.45 (3.34 to 9.55)	0.004	3.39 (3.16 to 3.62)	< 0.001	3 (2.97 to 3.03)	< 0.001	0.51 (− 0.13 to 1.14)	0.09	5.61 (4.96 to 6.28)	< 0.001
β₁	− 0.91 (− 2.67 to 0.86)	0.23	0.33 (0.18 to 0.48)	0.004	0.18 (0.15 to 0.21)	< 0.001	0.17 (− 0.18 to 0.52)	0.25	0.35 (0.06 to 0.64)	0.03
β₂	− 3.24 (− 10.12 to 3.64)	0.26	− 0.67 (− 1.28 to − 0.06)	0.04	− 1.16 (− 1.44 to − 0.88)	< 0.001	0.17 (− 1.07 to 1.41)	0.72	− 4.64 (− 5.6 to − 3.86)	< 0.001
β₃	1.3 (− 0.37 to 2.97)	0.10	− 0.62 (− 0.82 to − 0.43)	< 0.001	− 0.67 (− 0.77 to − 0.58)	< 0.001	0.05 (− 0.5 to 0.59)	0.82	− 0.55 (− 0.84 to − 0.26)	0.006

β₀ baseline incidence, β₁ baseline trend, β₂ change in incidence after intervention, β₃ change in trend after intervention, CI confidence interval, CRO-R Eco ceftriaxone-resistant E. coli, ETP-R Kpn ertapenem-resistant K. pneumoniae, MEM-R Aba meropenem-resistant A. baumannii, MEM-R Pae meropenem-resistant P. aeruginosa, OXA-R Sau oxacillin-resistant S. aureus

ISSN: 1471-2334