Fig. 3

Receiver operating characteristic area under the curve showing the discriminative performance of 3 different algorithms. A Predictive performance for the primary set. B Predictive performance for the validation set. The red line represents the ROC and AUC of tuberculosis nomogram, The green line represents the ROC and AUC of XPHACTOR study rule (included ART status, CD4 count, BMI, and the number of WHO symptoms), The blue line represents the ROC and AUC of W4SS algorithm. The vertical lines show the comparison between different algorithm AUCs, the red vertical lines with asterisk were AUC difference significant p < 0.05, the black vertical line was insignificant and p > 0.05. ROC receiver operating characteristic curve, AUC area under the curve, W4SS WHO-recommended four symptom screen