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Table 1 Comparison of baseline FT3, FT4, FT3/FT4 ratio, TSH, biochemical indicators and physical parameters in survivors and nonsurvivors [mean ± SD or median (Q25–Q75)]

From: Low serum free triiodothyronineis level predicts worse outcome of patients with severe fever with thrombocytopenia syndrome

Parameters

Survivors

nonsurvivors

controls

*p value

N (%)

173 (83.6)

34 (16.4)

30

Age (year)

60.9 ± 10.9##

71.4 ± 10.8###

55.1 ± 8.1

 < 0.0001

M/F (%)

84/89(48.6/51.4)

25/9 (73.5/26.5)

13/17(43.3/56.7)

0.013

FT3 (pmol/L)

2.78 (2.25, 3.44)###

2.24 ± 0.42###

4.40 ± 0.83

 < 0.0001

Prevalence of low serum FT3 (%)

71/172 (41.3)###

27/33(81.8)###

2/30(6. 7)

 < 0.0001

FT4 (pmol/L)

11.05 (9.93, 11.15)###

(n = 100)

10.87 ± 2.08###

(n = 26)

14.23 ± 2.01

0.37

FT3/FT4 ratio

0.25 ± 0.06###

(n = 100)

0.22 ± 0.06###

(n = 26)

0.32 ± 0.07

0.016

TSH ( uIU/ml)

1.37 (0.89, 1.96)

(n = 98)

0.61 (0.41, 1.06)##

(n = 24)

1.11 (0.86,1.72)

 < 0.0001

TCH (mmol/L)

3.5 (3.0, 4.18)

3.2 (2.6, 3.9)

0.084

Hs-CRP (mmol/L)

5 (1.8,13.3)

9 (5.3,41.0)

0.008

Pulse (beats/min)

74 (67,82)

84.0 ± 11.6

 < 0.0001

Baseline body tempreture (℃)

37.2 (36.3, 38.3)

37.5 (36.7, 38.5)

0.233

Highest

body tempreture (℃)

38.9 (38.5, 39)

39 (38.5,39.2)

0.42

Ctnl (pg/ml)

0.41(0.03, 33.5)

23.9(0.25, 214.6)

0.011

CK(U/L)

473 (178.9, 1027.4)

1199.5(485.3, 3523.5)

 

0.001

CK-MB(U/L)

33.7(21.3, 48.6)

59.1(31.7, 118.5)

 

0.001

LDH(U/L)

575.0 (386.1, 867.2)

942.2 (636.6, 1302.8)

 

0.004

HBDH(U/L)

404.3 (280.6, 566.8)

594.6 (438.1, 1114.3)

 

0.002

Incidence of neurological symptoms (%)

63/173 (36.4)

30/34 (88.2)

 

 < 0.0001

  1. FT3 free triiodothyronine; FT4 free tetraiodothyroxine; TSH thyroid stimulating hormone; TCH total cholesterol; Hs-CRP high-sensitivity C-reactive protein; MAP mean arterial pressure; Ctnl cardiac troponin; CK Creatine kinase; LDH lactate dehydrogenase; HBDH hydroxybutyrate dehydrogenase
  2. *Comparison between survivors and non-survivors
  3. ###p < 0.001, ##p < 0.01, #p < 0.05 in comprison with control