| Univariable | Multivariable | ||
---|---|---|---|---|
SHR (95% CI) | P | aSHR (95% CI) | P | |
At ART initiation | Â | Â | Â | Â |
 Males | 1.22 (0.86–1.77) | 0.300 |  |  |
 CDC classification C | 4.02 (2.75–5.88) |  < 0.001 | 1.22 (0.25–5.97) | 0.802 |
 History of prior TB | 0.78 (0.34–1.78) | 0.556 |  |  |
Time updated variables | Â | Â | Â | Â |
 Age | 0.98 (0.96–1.00) | 0.195 |  |  |
BMI Classification | Â | Â | Â | Â |
 < 18.5 kg/m2 | 9.59 (3.45–26.64) |  < 0.001 | 8.21 (2.43–27.73) | 0.001 |
 18.5–23 kg/m2 | 1 |  | 1 |  |
 > 23 kg/m2 | 0.94 (0.29–3.00) | 0.912 | 0.71 (0.18–2.84) | 0.628 |
Smoking history | Â | Â | Â | Â |
 Non-smoker or ex-smoker | 1 |  |  |  |
 Current smoker | 1.13 (0.77–1.66) | 0.520 |  |  |
Alcohol consumption | Â | Â | Â | Â |
 No alcohol use in past 3 months | 1 |  |  |  |
 Alcohol use in past 3 months | 0.84 (0.57–1.24) | 0.390 |  |  |
History of substance use | 2.11 (0.91–4.88) | 0.078 | 6.03 (1.16–31.21) | 0.032 |
History of close contact TB cases | 1.64 (0.98–2.74) | 0.058 | 1.71 (0.37–7.78) | 0.489 |
Hypertension | 1.13 (0.68–1.88) | 0.621 |  |  |
Diabetes mellitus | 0.44 (0.14–1.42) | 0.171 |  |  |
Hepatitis B co-infection | 0.93 (0.52–1.64) | 0.807 |  |  |
Hepatitis C co-infection | 1.39 (0.79–2.42) | 0.246 |  |  |
CD4 cell count (cell/m3) | Â | Â | Â | Â |
• < 50 | 12.02 (5.96–24.22) |  < 0.001 | 18.23 (3.35–99.16) | 0.001 |
• 51–200 | 8.51 (4.97–14.53) |  < 0.001 | 5.43 (0.98–29.92) | 0.052 |
• 201–350 | 2.32 (1.31–4.11) | 0.004 | 1.99 (0.35–11.07) | 0.432 |
• > 350 | 1 |  | 1 |  |
HIV-RNA ≥ 50 copies/mL | 2.55 (0.53–12.25) | 0.243 |  |  |