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Table 4 Factors associated with incident tuberculosis among participants from a competing risks regression model

From: Incidence and factors associated with active tuberculosis among people living with HIV after long-term antiretroviral therapy in Thailand: a competing risk model

 

Univariable

Multivariable

SHR (95% CI)

P

aSHR (95% CI)

P

At ART initiation

    

 Males

1.22 (0.86–1.77)

0.300

  

 CDC classification C

4.02 (2.75–5.88)

 < 0.001

1.22 (0.25–5.97)

0.802

 History of prior TB

0.78 (0.34–1.78)

0.556

  

Time updated variables

    

 Age

0.98 (0.96–1.00)

0.195

  

BMI Classification

    

 < 18.5 kg/m2

9.59 (3.45–26.64)

 < 0.001

8.21 (2.43–27.73)

0.001

 18.5–23 kg/m2

1

 

1

 

 > 23 kg/m2

0.94 (0.29–3.00)

0.912

0.71 (0.18–2.84)

0.628

Smoking history

    

 Non-smoker or ex-smoker

1

   

 Current smoker

1.13 (0.77–1.66)

0.520

  

Alcohol consumption

    

 No alcohol use in past 3 months

1

   

 Alcohol use in past 3 months

0.84 (0.57–1.24)

0.390

  

History of substance use

2.11 (0.91–4.88)

0.078

6.03 (1.16–31.21)

0.032

History of close contact TB cases

1.64 (0.98–2.74)

0.058

1.71 (0.37–7.78)

0.489

Hypertension

1.13 (0.68–1.88)

0.621

  

Diabetes mellitus

0.44 (0.14–1.42)

0.171

  

Hepatitis B co-infection

0.93 (0.52–1.64)

0.807

  

Hepatitis C co-infection

1.39 (0.79–2.42)

0.246

  

CD4 cell count (cell/m3)

    

• < 50

12.02 (5.96–24.22)

 < 0.001

18.23 (3.35–99.16)

0.001

• 51–200

8.51 (4.97–14.53)

 < 0.001

5.43 (0.98–29.92)

0.052

• 201–350

2.32 (1.31–4.11)

0.004

1.99 (0.35–11.07)

0.432

• > 350

1

 

1

 

HIV-RNA ≥ 50 copies/mL

2.55 (0.53–12.25)

0.243

  
  1. SHR sub-distribution hazard ratio