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Table 2 Data of the five women with known viral load at delivery

From: New diagnosis of mother-to-child transmission of HIV in 8 Latin-American countries during 2018

 

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Mother

Age (years)

27

33

26

34

35

Timing of HIV diagnosis

Delivery

3rd trimester

Pregestational

Delivery

Pregestational

CD4 count in third trimester (cel/µl)

200–300

200–300

 > 750

 < 200

 < 200

Viral load at childbirth (copies/ml)

10,000–100,000

10,000–100,000

 < 50

 > 100,000

 < 50

Gestational age at birth (weeks)

37

37

37

37

38

Type of delivery

Vaginal

CS

CS

CS

CS

ART before pregnancy

No

No

No

No

Yes (ZDV + 3TC

 + EFV)

ARV prophylaxis at delivery

No

n/d

n/d

n/d

ZDV iv

Child

Birth weight (grams)

2000–4000

2000–4000

2000–4000

2000–4000

2000–4000

Type of ARV prophylaxis in the newborn

ZDV + 3TC

 + RTG

ZDV + 3TC

3TC

n/d

ZDV

Maternal breastfeeding

No

No

No

n/d

n/d

Age at diagnosis (months)

0.5

2

3

10

59

Viral load at diagnosis (copies/ml)

10,000–100,000

10,000–100,000

10,000–100,000

 > 100,000

 > 100,000

CD4 count at diagnosis (cel/µl)

 > 750

 > 750

 > 750

 > 750

 > 750

CDC clinical classification of HIV at diagnosis

B

N

A

A

C

  1. HIV human immunodeficiency virus, CS cesarean section, ART antiretroviral therapy, ZDV zidovudine, 3TC lamivudine, EFV efavirenz, ARV antiretroviral prophylaxis, n/d no data available, RTG raltegravir, CDC Centers for Diseases Control and Prevention