The impact of nucleic acid testing to detect human immunodeficiency virus, hepatitis C virus, and hepatitis B virus yields from a single blood center in China with 10-years review

Table 2 Numbers and proportions of donations in NAT detection and the results of NAT yields in the seven blood services

		Blood services							Method		Overall
		Hangzhou	Xiaoshan	Jiande	Yiwu	Shaoxing	Jiaxing	Huzhou	TMA	PCR
Years	2010	46,853	/	/	/	/	/	/	46,853	/	46,853
	2011	131,594	/	/	/	/	/	/	131,594	/	131,594
	2012	125,656	/	/	/	/	/	/	125,656	/	125,656
	2013	129,668	479	291	2317	/	/	/	105,668	27,087	132,755
	2014	133,738	13,680	11,844	11,378	/	/	/	119,301	51,339	170,640
	2015	135,470	13,546	12,724	11,410	/	/	/	106,505	66,645	173,150
	2016	139,646	13,846	12,865	13,111	41,526	41,699	27,080	106,494	183,279	289,773
	2017	143,769	14,110	12,419	13,797	48,194	50,571	32,194	158,791	156,263	315,054
	2018	149,465	15,749	13,085	15,412	50,515	54,843	33,291	136,568	195,792	332,360
	2019	161,135	16,400	13,849	15,896	52,741	59,739	34,100	122,925	230,935	353,860
Overall	Numbers	1,296,994	87,810	77,077	83,321	192,976	206,852	126,665	1,160,355	911,340	2,071,695
Overall	Proportions	62.61%	4.24%	3.72%	4.02%	9.31%	9.98%	6.11%	56.01%	43.99%	100.00%
Non-discriminating reactive*	Numbers	1056	101	154	184	124	88	56	1763	/	1763
Non-discriminating reactive*	NAT yields (per million)	814.19	1150.21	1998.00	2208.33	642.57	425.42	442.11	1519.36	/	850.99
HBV	Numbers	1146	109	199	132	264	212	140	1279	923	2202
HBV	NAT yields (per million)	883.58	1241.32	2581.83	1584.23	1368.05	1024.89	1105.28	1102.25	1012.79	1062.90
HCV	Numbers	2	0	0	0	0	0	0	2	0	2
HCV	NAT yields (per million)	1.54	0	0	0	0	0	0	1.72	0	0.97
HIV	Numbers	3	0	0	0	0	0	0	2	1	3
HIV	NAT yields (per million)	2.31	0	0	0	0	0	0	1.72	1.10	1.45
ALL NAT⁺ELISA⁻	Numbers	2207	210	353	316	388	300	196	3046	924	3970
ALL NAT⁺ELISA⁻	NAT yields (per million)	1701.63	2391.53	4579.84	3792.56	2010.61	1450.31	1547.39	2625.06	1013.89	1916.31

Bold values indicate the total NAT positive numbers and NAT yields in different regions
HBV Hepatitis B virus, HCV Hepatitis C virus, HIV Human immunodeficiency virus, ELISA enzyme linked immunosorbent assay, NAT nucleic acid amplification testing, PCR polymerase chain reaction, TMA transcription-mediated amplification
^*The donations were reactive in ID-NAT screening assays but not in discriminatory assays using TMA method

ISSN: 1471-2334