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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Comparison and development of a metagenomic next-generation sequencing protocol for combined detection of DNA and RNA pathogens in cerebrospinal fluid

Fig. 3

RPMratio of target pathogen in each sample. A RPMratio of SPN and E.coli. There were three concentration gradients in y-axis: 103 CFU / ml, 5 × 104 CFU / ml and 105 CFU / ml. The red solid dots represent RPMratio of E.coli by microbial DNA, total DNA, total Na and total RNA. The blue solid dots represent RPMratio of SPN by microbial DNA, total DNA, total Na and total RNA. The dashed line highlights the threshold of ratio = 10. B RPMratio of EBV and EV71. There were two concentration gradients in y-axis: 5 × 103 copies/ml, 5 × 105 copies/ ml. The red solid dots represent RPMratio of EBV by Total DNA, Total NA, Total RNA and WTA. The blue solid dots represent RPMratio of EV71 by Total DNA, Total NA, Total RNA and WTA. C Heat map summarizing RPMratio of E. coli and SPN in sample 1–6. D Heat map summarizing RPMratio of EBV and EV71 in sample 10–13. The position of missing samples is filled with gray

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