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Table 1 Characteristics of hospitalized COVID-19 patients treated with or without methylprednisolone (n = 759)

From: Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia

Level No methylprednisolone (n = 380) Methylprednisolone (n = 379) P value
Count (%) Count (%)
Age ≥ 60.0 years 254 (66.67) 244 (64.55) 0.2436
Male 237 (62.20) 242 (64.02) 0.5775
Black 58 (15.30) 44 (11.80) 0.2500
White 178 (46.97) 160 (42.90) 0.2500
Asian/Indian 25 (6.60) 36 (9.65) 0.2500
Hispanic 118 (31.13) 133 (35.66) 0.2500
BMI ≥ 30 kg/m2 179 (46.98) 181 (47.88) 0.6767
Smoker (former or current) 77 (21.69) 88 (25.96) 0.2334
Fever 250 (65.79) 294 (77.78) 0.0003
Shortness of breath 248 (65.09) 298 (79.05)  < 0.0001
Cough 242 (63.68) 270 (71.43) 0.0191
Altered mental status 63 (16.54) 41 (10.85) 0.0032
GI 76 (20.00) 81 (21.49) 0.5211
Anosmia or ageusia 6 (1.59) 9 (2.45) 0.5930
Duration of symptoms PTA 5.00 (2.00,7.00) 5.00 (3.00,7.00) 0.0699
Duration > 7 days 59 (18.91) 75 (21.99) 0.2864
Diabetes 144 (37.53) 139 (36.51) 0.6521
COPD 20 (5.25) 28 (7.41) 0.2482
Asthma 24 (6.30) 37 (9.81) 0.0741
Hypertension 225 (59.06) 219 (57.94) 0.5525
Cancer 43 (11.29) 43 (11.38) 0.9013
Cerebrovascular accident 18 (4.74) 14 (3.70) 0.3692
Coronary artery disease 29 (7.61) 28 (7.41) 0.8886
Arrhythmia 41 (10.79) 30 (7.94) 0.1213
Chronic kidney disease 28 (7.35) 31 (8.20) 0.6682
Rheumatologic disorder 10 (2.62) 19 (5.04) 0.0588
qSOFA 0 224 (58.49) 222 (58.42) 0.7647
qSOFA 1 130 (33.94) 130 (34.21) 0.7647
qSOFA 2 28 (7.31) 26 (6.84) 0.7647
qSOFA 3 1 (0.26) 2 (0.53) 0.7647
Temperature 98.80 (97.70,100.40) 99.30 (98.00,100.70) 0.1284
Heart rate 95.00 (84.00,108.00) 97.00 (86.00,108.00) 0.1438
Arterial pressure 92.33 (83.33,100.50) 90.67 (81.83,99.33) 0.0870
Respiratory rate 19.00 (18.00,22.00) 20.00 (18.00,22.00) 0.3231
O2 Sat < 94% 215 (56.43) 217 (57.41) 0.6733
Nasal cannula 160 (82.05) 131 (65.83) 0.2500
Venti mask 2 (1.03) 3 (1.51) 0.2500
High flow 6 (3.08) 15 (7.54) 0.2500
CPAP 1 (0.51) 2 (1.01) 0.2500
BiPAP 0 (0.00) 2 (1.01) 0.2500
Non-rebreather 26 (13.33) 46 (23.12) 0.2500
Mechanical ventilation 35 (11.15) 129 (39.33)  < 0.0001
WBC 6.60 (5.10,9.20) 6.50 (5.10,9.50) 1.0000
HGB 13.40 (12.30,14.50) 13.50 (12.20,14.70) 0.6746
PLT 203.00 (161.00,257.00) 189.50 (147.00,252.00) 0.2736
ALC 0.90 (0.60,1.30) 0.80 (0.60,1.10) 0.0031
IL6 12.00 (5.00,39.00) 15.00 (5.00,36.00) 0.2678
CRP 9.88 (4.99,17.31) 12.67 (6.84,19.08) 0.0047
D-dimer 1.09 (0.65,2.20) 1.44 (0.72,3.13) 0.1155
Ferritin 729.50 (325.50,1404.00) 867.00 (418.00,1548.00) 0.0675
Creatinine 1.01 (0.80,1.50) 1.01 (0.80,1.35) 0.2630
Troponin 0.03 (0.01,0.30) 0.02 (0.01,0.09) 0.0732
BNP 131.85 (40.30,1000.55) 88.80 (26.20,362.00) 0.2110
Hydroxychloroquine 269 (71.93) 317 (88.55)  < 0.0001
Azithromycin 255 (68.55) 264 (73.54) 0.0728
Remdesivir 3 (0.82) 10 (2.82) 0.0196
Tocilizumab 13 (3.53) 63 (17.65)  < 0.0001