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Table 4 Baseline clinical characteristics and laboratory parameters by NLR < 4.19 and NLR ≥ 4.19 groups

From: Neutrophil-to-lymphocyte ratio is associated with 28-day mortality in patients with severe fever with thrombocytopenia syndrome

Variable

NLR ≥ 4.19

(n = 30)

NLR < 4.19

(n = 152)

P Value

Demographics

   

 Age, years

62.97 ± 13.43

58.98 ± 12.54

0.118

 Male, sex, n (%)

17 (56.7)

71 (46.7)

0.319

Chronic comorbidities

   

 HTN, n (%)

9 (30.0)

33 (21.7)

0.325

 DM, n (%)

2 (6.7)

11 (7.2)

0.912

 COPD, n (%)

1 (3.3)

1 (7.0)

0.744

 CAD, n (%)

1 (3.3)

1 (7.0)

0.744

Clinical manifestations

   

 Fever, n (%)

29 (96.7)

150 (98.7)

0.993

 Vomiting, n (%)

8 (26.7)

28 (18.4)

0.300

 Diarrhea, n (%)

5 (16.7)

42 (27.6)

0.210

 Headache, n (%)

10 (33.3)

52 (34.2)

0.926

 Abdominal pain, n (%)

2 (6.7)

16 (10.5)

0.755

 Cough, n (%)

7 (23.3)

23 (15.1)

0.269

 Lymphadenopathy, n (%)

12 (40.0)

56 (36.8)

0.744

 Petechiae, n (%)

7 (23.3)

21 (13.8)

0.187

 GCS scores, mean ± SD

11.76 ± 3.26

13.59 ± 2.43

0.006

Laboratory parameters

   

 RDW, mean ± SD, %

13.23 ± 0.93

13.28 ± 1.22

0.840

 PLT count, median (IQR), ×109/L

55.00 (36.00, 88.50)

48.50 (34.00, 77.50)

0.327

 PT, mean ± SD, s

12.35 ± 2.73

11.30 ± 1.06

0.059

 APTT, mean ± SD, s

43.07 ± 15.66

39.81 ± 12.57

0.121

 ALT, median (IQR), U/L

62.00 (36.98, 87.60)

73.30 (47.30, 123.50)

0.093

 AST, median (IQR), U/L

98.75 (73.90, 220.63)

132.60 (71.7, 262.90)

0.534

 LDH, median (IQR), U/L

755.00 (548.25, 1417.25)

747.50 (399.5,1282.25)

0.668

 TBil, median (IQR), μmol/L

10.00 (6.65, 24.45)

10.00 (6.90,16.40)

0.425

 DBil, median (IQR), μmol/L

4.45 (2.43, 10.78)

4.20 (2.50, 6.05)

0.243

 SCr, mean ± SD, μmol/L

80.72 ± 65.32

62.31 ± 35.75

0.144

 BUN, median (IQR), mmol/L

4.70 (3.85,6.30)

3.50 (2.70, 4.90)

0.002

Complications

   

 MODS, n (%)

16 (53.3)

35 (23.0)

0.001

 Duration of hospital

   

Length of hospital stay, median (IQR) days

   

 Outcome

7.00 (5.75, 12.00)

9.50 (7.00, 12.00)

0.047

 28-day mortality, n (%)

13 (43.3)

11 (7.2)

0.001

  1. BUN blood urea nitrogen, COPD chronic obstructive pulmonary disease, CAD coronary artery disease, DIC disseminated intravascular coagulation, DM diabetes mellitus, GCS Glasgow coma scale, HTN hypertension, MODS multiple organ dysfunction syndrome, SCr serum creatinine, UA uric acid, RDW red cell volume distribution width, PLT platelet, APTT activated partial thromboplastin time, PT prothrombin time, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, TBil total bilirubin, DBil direct bilirubin
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BMC Infectious Diseases

ISSN: 1471-2334

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