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Table 2 Antibiotic susceptibility results of pneumococcal isolates from children with invasive pneumococcal disease

From: Clinical characteristics, antimicrobial resistance, and risk factors for mortality in paediatric invasive pneumococcal disease in Beijing, 2012–2017

Antibiotica

No. of isolates (%)b

Total no. of isolates

Susceptible

Intermediate

Resistant

Nonsusceptible

(R + I)

Penicillin

     

 Meningitisc

16(28.1)

0

41(71.9)

41 (71.9)

57

 Nonmeningitis

67 (51.9)

51 (39.5)

11 (8.5)

62 (48.1)

129

Cefotaxime

     

 Meningitisc

17 (35.4)

23 (47.9)

8 (16.7)

31 (64.6)

48

 Nonmeningitis

74 (61.7)

27 (22.5)

19 (15.8)

46 (37.5)

120

Cefepime

     

 Meningitisc

10 (23.8)

12 (28.6)

20 (47.7)

32 (76.2)

42

 Nonmeningitis

49 (49.5)

42 (42.4)

8 (19.0)

50 (50.1)

99

 Erythromycin

4 (2.6)

0

152 (97.4)

152 (97.4)

156

 Clindamycin

4 (2.6)

0

149 (97.4)

149 (97.4)

153

 Tetracycline

14 (9.0)

14 (9.0)

128 (82.1)

128 (91.0)

156

 SMZ-Co

47 (26.3)

22 (12.3)

110 (61.5)

110 (73.7)

179

 Chloramphenicol

166 (93.3)

0

12 (6.7)

12 (6.7)

178

 Levofloxacin

155 (100.0)

0

0

0 (0)

155

 Meropenem

39 (39.0)

35 (35.0)

26 (26.0)

61 (61)

100

 Vancomycin

181 (100.0)

0

0

0 (0)

181

 Linezolid

181 (100.0)

0

0

0 (0)

181

  1. aSMZ-Co, compound sulfamethoxazole
  2. bData are presented as the number of cases (%) for categorical variables
  3. CFor patients clinically diagnosed with meningitis and with drug sensitivity test results, the strain is derived from CSF or other sterile site samples, where priority is given to the inclusion in CSF isolates. Other sterile site samples are interpreted according to meningitis resistance criteria