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Table 2 Multiple antibiotic resistance in ambulatory-onset urine Enterobacterales isolates (2011–2020)

From: A multicenter analysis of trends in resistance in urinary Enterobacterales isolates from ambulatory patients in the United States: 2011–2020

ESBL resistance profile

n

Resistance to additional antimicrobials

n (%)

FQ

TMP/SMX

NFT

Beta-lactams

ESBL only

145,448 (100%)

101,971 (70.1%)

87,145 (59.9%)

48,470 (33.5%)

134,038 (92.2%)

ESBL + FQ

101,971 (100%)

 

73,363 (71.9%)

38,372 (37.6%)

101,222 (99.3%)

ESBL + TMP/SMX

87,145 (100%)

73,363 (84.2%)

 

35,619 (40.9%)

86,738 (99.5%)

ESBL + NFT

48,740 (100%)

38,372 (78.7%)

35,619 (73.1%)

 

48,497 (99.5%)

ESBL + FQ + TMP/SMX

73,363 (100%)

  

30,784 (42.0%)

73,030 (99.5%)

ESBL + FQ + TMP/SMX + NFT

30,784 (100%)

   

30,698 (99.7%)

  1. Percentages are based on the number of isolates with the specified ESBL resistance profile (column labeled “n”)
  2. ESBL extended-spectrum beta-lactamase-producing phenotype, FQ fluoroquinolones, NFT nitrofurantoin, NS not susceptible, TMP/SMX trimethoprim/sulfamethoxazole