Skip to main content

Table 3 Proportion of different types of sequelae among the 869 IMD survivors by factor from 2005–2020

From: Risk of sequelae after invasive meningococcal disease

 

Death within 30 days, n (%)

Total number of survivors

Hearing loss

Epilepsy

Learning disabilities*

Headache**

Visual defects and loss of vision

Abnormal involuntary movements

Other—the nervous and movement system

Arthritis***

Proportion of IMD survivors with sequelae (%)

Age group (years)

 0–5

11 (4%)

281

6.8

3.9

5.3

1.4

4.3

1.1

0.4

1.4

 6–15

2 (1%)

142

9.2

6.3

5.6

2.8

2.8

0.7

0.7

0.7

 16–25

14 (8%)

179

8.4

5.6

2.2

6.7

2.2

1.7

1.1

0.6

 26–65

10 (6%)

163

7.4

8

2.5

4.9

1.8

3.1

3.7

3.1

 66+

29 (28%)

104

10.6

3.8

 

1.9

1

1

1.9

 

Serogroup^

 B

26 (7%)

379

8.7

5.8

4.2

4

3.4

1.1

1.3

0.8

 C

20 (9%)

232

10.8

4.3

3.9

2.6

3

1.7

1.3

1.7

 W

10 (14%)

71

4.2

2.8

 

1.4

2.8

1.4

 

2.8

 Y

6 (11%)

54

3.7

5.6

 

5.6

 

1.9

1.9

1.9

 Other

4 (3%)

131

6.1

6.9

4.6

3.8

1.5

2.3

2.3

0.8

Clinical presentation

 Meningitis only

11 (3%)

315

9.8

6.7

2.2

4.8

2.2

1.3

2.2

0.6

 Meningitis and septicaemia

27 (11%)

245

9

6.1

6.5

2

4.1

2

1.6

2

 Septicaemia only

26 (9%)

285

5.6

3.9

2.8

3.5

2.1

1.4

0.4

0.7

 Other invasive disease

2 (8%)

24

8.3

   

4.2

  

8.3

Total

66 (8%)

869

8.2

5.4

3.6

3.5

2.8

1.5

1.4

1.3

 

Vascular disorders of the brain

Sequelae others

Mental retardation

Embolism, thrombosis, amputation, gangrene and skin necrosis

(CNS—abnormal US)

Hydrocephalus

Palsy****

Walking difficulties and mobility disorders

Rehabilitation*****

Proportion of IMD survivors with sequelae (%)

Age group (years)

 0–5

 

0.7

0.7

 

0.4

   

0.7

 6–15

 

1.4

0.7

     

0.7

 16–25

1.7

1.1

1.1

1.1

 

0.6

  

2.8

 26–65

1.2

0.6

0.6

0.6

0.6

   

4.9

 66+

2.9

1

 

1

1

1

1.9

1

8.7

Serogroup^

 B

0.8

1.1

0.8

0.3

0.3

 

0.3

 

3.7

 C

1.7

1.3

1.3

0.9

 

0.9

0.4

0.4

2.2

 W

 

1.4

      

4.2

 Y

1.9

  

1.9

1.9

   

1.9

 Other

    

0.8

   

1.5

Clinical presentation

 Meningitis only

1.6

0.6

0.3

  

0.3

0.6

 

3.2

 Meningitis and septicaemia

1.2

2

1.2

0.4

0.4

0.4

  

1.6

 Septicaemia only

 

0.4

0.7

1.1

0.7

  

0.4

3.5

 Other invasive disease

        

4.2

Total

0.9

0.9

0.7

0.5

(0.3)

0.2

0.2

0.1

2.9

  1. ^Two cases had unknown serogroup
  2. *Significant difference in distribution between age groups (p = 0.011)
  3. **Significant difference in distribution between age groups (p = 0.036)
  4. ***Significant difference in distribution between clinical presentation (p = 0.019)
  5. ****Significant difference in distribution between age groups (p = 0.005)
  6. *****Significant difference in distribution between age groups (p < 0.000)