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Table 3 Bivariate analysis to determine variables associated with development of DNAemia ≥ 4000UI/ml

From: Incidence of Cytomegalovirus disease and viral replication kinetics in seropositive liver transplant recipients managed under preemptive therapy in a tertiary-care center in Mexico City: a retrospective cohort study

Variable

Total N = 113

VL ≥ 4000 UI/ml

N = 23

VL < 4000 UI/ml

N = 90

OR (CI95%)

p

Age

52 (41–59)

55 (39–62)

51 (41–58)

1.01 (0.97–1.06)

0.34

Female sex

57 (50%)

13 (56%)

44 (49%)

1.35 (0.54.3.41)

0.51

Hepatitis C

23 (20%)

3 (9%)

10 (22%)

0.52 (0.14–1.94)

0.33

Cryptogenic cirrhosis

24 (21%)

3(13%)

21 (23%)

0.49 (0.13–1.82)

0.28

Autoimmune hepatitis

20 (18%)

7 (30%)

13 (14%)

2.58 (0.89–7.51)

0.08

Hepatocellular carcinoma

25 (22%)

5 (22%)

20 (22%)

0.97 (0.32–2.94)

0.96

Child–Pugh C

62 (55%)

12 (52%)

50 (55%)

0.87 (0.34–2.18)

0.77

MELD

35 (31%)

7 (30%)

28 (31%)

0.96 (0.35–2.61)

0.95

Donor CMV IgG positive

72/83 (87%)

18/19 (95%)

54/64 (84%)

3.33 (0.39–27.87)

0.26

Surgical time > 7 h

27/109 (25%)

4/22 (18%)

23/87 (26%)

0.61 (0.18–2.01)

0.42

 > 6 blood cell transfused

24 (21%)

5 (22%)

19 (21%)

1.03 (0.34–3.15)

0.94

Reoperation

10 (9%)

1 (4%)

9 (10%)

0.4 (0.49–3.4)

0.4

Grade 3 AKI

25 (22%)

4 (17%)

21 (23%)

0.69 (0.21–2.25)

0.54

Posttransplant bacterial infection

27 (24%)

5 (22%)

22 (24%)

0.85 (0.28–2.58)

0.78

Viral load growth rate > 0.16 UI/ml/day

37/70 (53%)

15/19 (79%)

22/51 (43%)

4.94 (1.43–16.98)

0.011

  1. Continuous variables are presented as medians and inter-quartile range. Categorical variables are presents as percentages
  2. VL viral load, MELD Model for End Stage Liver Disease, AKI acute kidney injury