Skip to main content

Table 2 Comparison of clinical parameters between the non-HCQ and HCQ groups

From: “H” is not for hydroxychloroquine—“H” is for heparin: lack of efficacy of hydroxychloroquine and the role of heparin in COVID-19—preliminary data of a prospective and interventional study from Brazil

COVID-19 patients (N = 154)

 

Demographics

Non-HCQ N = 59 (%)

HCQ N = 95 (%)

p value

 

Gender

    

 Male

36 (61.0)

51 (53.7)

0.372

 

 Female

26 (39.0)

44 (46.3)

  

Age (years)

61 (22–89)

59 (21–90)

0.254

 

Systemic Arterial Hypertension

30 (50.8)

48 (50.5)

0.969

 

Type 2 diabetes mellitus

19 (32.2)

31 (32.6)

0.956

 

Obesity

7 (11.9)

17 (17.9)

0.316

 

COPD

2 (3.4)

4 (4.2)

0.798

 

Asthma

0

5 (5.3)

0.073

 

Kidney disease

6 (10.2)

7 (7.4)

0.543

 

Hepatic disease

0

3 (3.2)

0.168

 

Cardiopathy

6 (10.2)

7 (7.4)

0.543

 

Cancer

20 (33.9)

12 (12.6)

0.002

 

Autoimmune disease

2 (3.4)

4 (4.2)

0.798

 

Dyslipidemia

4 (6.8)

3 (3.2)

0.294

 

Neuro and psychiatric disorders

7 (11.9)

5 (5.3)

0.137

 

Smoking

    

 Yes

 Ex

3 (5.1)

7 (11.9)

7 (7.4)

4 (4.2)

0.183

 

Alcoholic

    

 Yes

 Ex

1 (1.7)

4 (6.8)

2 (2.1)

0

0.036

 

Comorbidities

55 (93.2)

81 (85.3)

0.135

 

Comorbidities ≥ 2

43 (78.2)

57 (70.4)

0.311

 

Pulmonary involvement > 50%

20 (42.6)

39 (55.7)

0.163

 

Pneumonia

55 (93.2)

94 (98.9)

0.071

 

ICU admission

41 (69.5)

76 (80.0)

0.138

 

Oseltamivir

33 (55.9)

85 (89.5)

 < 0.001

 

Azithromycin

39 (66.1)

91 (95.8)

 < 0.001

 

Corticosteroids

40 (67.8)

75 (78.9)

0.122

 

Heparin

52 (88.1)

94 (98.9)

0.005

 

Endotracheal Intubation

12 (20.3)

33 (34.7)

0.056

 

DVT

1 (1.7)

1 (1.1)

1.000

 
  1. Comparison of categorical variables using the Chi-square test between non-HCQ and HCQ groups. ICU Intensive care unit, DVT Deep vein thrombosis, N number of individuals, % percentage