Table 6 Plasma D-dimer Studies
References | Country | PJI/AL | Study design | Site | Age (PJI/AL) | BMI (PJI/AL) | Cut-off ng/mL | Standard Reference | Sensitivity (%) | Specificity (%) | Exluded hipercoagulation disorder | Excluded inflammatory arthritis |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fu et al. [24] | China | 15/15 | Prospective | H/K | 65.6/65.4 | 25.7/24.7 | 850 | MSIS | 66.67 | 60 | No | Yes |
Li et al. [25] | China | 76/363 | Retrospective (multicentre) | H/K | 63.7/61.3 | 25.0/25.1 | 1250 | ICM | 64.5 | 65 | No | No |
Xu et al. [26] | China | 129/189 | Retrospective | H/K | NA | NA | 1020 | MSIS | 68.29 | 50.70 | No | No |
Chen et al. [30] | China | 30/60 | Retrospective (Matched study) | H/K | 61.5/67.7 | 26.0/24.9 | 1690 | MSIS | 66.7 | 76.7 | No | No |
Wu et al. [27] | China | 35a27b/81 | Retrospective | H/K | 62.6/69.1 | 24.7/24.5 | 410 | MSIS | 75.8 | 67 | No | No |
Ackmann et al. [28] | Europe (Germany) | 52/67 | Retrospective | H/K | 70.5/68 | 30.9/28.4 | 2750 | MSIS | 38 | 94 | Yes | Yes |
Huang et al. [29] | China | 47/38 | Retrospective | H/K | 63.7/66.8 | NA | 1170 | MSIS | 60 | 85 | Yes | Yes |
Present study | Europe (Spain) | 39/141 | Prospective | H/K | 69.2/66.5 | 30.6/29.9 | 1167 | IDSA | 71.8 | 75.3 | Yes | No |