Table 3 Diagnostic Accuracy of Combined Preoperative Tests according to type of PJI
Markers | Specificity (%) (95% CI) | Sensitivity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | AUC (95% CI) |
|---|---|---|---|---|---|
D-dimer + CRP | |||||
All PJI patients | 92.7 (88.3–97) | 59 (43.5–74.4) | 69.7 (54–85.4) | 88.8 (83.6–94) | 0.885 (0.831–0.938) |
Early | 92.7 (88.3–97) | 57.1 (20.5–93.8) | 28.6 (4.9–52.2) | 97.7 (93–100) | 0.944 (0.902–0.985) |
Delayed | 92.7 (88.3–97) | 44.4 (12–76.9) | 28.6 (5–52.2) | 96.2 (91.6–100) | 0.914 (0.853–0.975) |
Late | 92.7 (88.3–97) | 65.2 (45.7–84.7) | 60 (40.8–79.2) | 94.1 (89.6–98.5) | 0.855 (0.782–0.928) |
D-dimer + ESR | |||||
All PJI patients | 88.3 (82.9–93.7) | 61.5 (46.3–76.8) | 60 (44.8–75.2) | 89 (83.5–94.4) | 0.812 (0.729–0.896) |
Early | 88.3 (82.9–93.7) | 71.4 (38–100) | 23.8 (5.6–42) | 98.4 (92–100) | 0.917 (0.856–0.978) |
Delayed | 88.3 (82.9–93.7) | 44.4 (12–76.9) | 20 (2.4–37.5) | 96 (89.9–100) | 0.872 (0.786–0.957) |
Late | 88.3 (82.9–93.7) | 65.2 (45.7–84.7) | 48.4 (30.8–66) | 93.8 (87.9–99.7) | 0.7358 (0.633–0.882) |
CRP + ESR | |||||
All PJI patients | 87.8 (82.4–93.3) | 76.9 (63.7–90.1) | 63.8 (50–77.6) | 93.2 (87.3–99) | 0.838 (0.757–0.919) |
Early | 87.8 (82.4–93.3) | 85.7 (59.8–100) | 26 (8.1–44) | 99,1 (92.77–100) | 0.903 (0.83–0.976) |
Delayed | 87.8 (82.4–93.3) | 77.7 (50.6–100) | 29.2 (11–47.3) | 98.4 (92–100) | 0.926 (0.869–0.984) |
Late | 87.8 (82.4–93.3) | 73.9 (56–91.8) | 50 (33.2–66.8) | 95.3 (89.2–100) | 0.783 (0.66–0.919) |