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Table 1 Baseline demographic and clinical characteristics of analytic cohort, bronchiectasis natural history study (n = 300)

From: The 6-minute walk test predicts mortality in a pulmonary nontuberculous mycobacteria-predominant bronchiectasis cohort

Characteristic N (%)
Follow up (years)–median [IQR] 4.1 [2.8–4.6]
Female 217 (72)
Age–median [IQR] 62 [50–69]
Died 21 (7)
Body Mass Index (kg/m)–median [IQR] 21.4 [19.8–24.2]
Fibrocavitary disease 44 (15)
FEV1% predicted–median [IQR] 72.5 [58–86.2]
DLCO adj% predicted–median [IQR] 64 [53.8–74]
C-reactive protein (mg/L)–median [IQR] 2.1 [0.8–6]
Comorbidities
 Asthma 57 (19)
 Cystic fibrosis 20 (7)
 Chronic obstructive pulmonary disease 12 (4)
 Pulmonary hypertension 8 (3)
 Primary ciliary dyskinesia 2 (1)
NTM positive since enrollmentb 219 (74)
 MACc 168 (57)
 M. abscessusd 97 (33)
 Other NTM species 65 (22)
NTM positive at study baseline 150 (51)
 MAC 96 (64)
 M. abscessus 62 (41)
 Other NTM species 24 (16)
AFB smear positive at study baseline 49 (17)
Non-NTM organisms at study baseline  
 Aspergillus 91 (31)
 Pseudomonas 53 (18)
 Staphylococcus aureus 17 (6)
 Stenotrophomonas 18 (6)
  1. Missing data: BMI: n = 5, Fibrocavitary disease: n = 35, FEV1: n = 12, DLCO: n = 16, C-reactive protein: n = 1, Microbiology: 6 patients without pulmonary cultures taken at NIH (unable to produce sputum after induction, appointment no-show)
  2. IQR interquartile range [25th percentile–75th percentile], BMI body mass index, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lungs for carbon monoxide, NTM nontuberculous mycobacteria, MACMycobacterium avium complex, AFB Acid-fast bacilli
  3. aExcludes M. gordonae
  4. bIncludes: Mycobacterium avium complex, Mycobacterium avium, Mycobacterium intracellulare/chimaera, Mycobacterium chimaera, Mycobacterium intracellulare
  5. cIncludes: Mycobacterium abscessus, Mycobacterium abscessus group, Mycobacterium massiliense, Mycobacterium chelonae, Mycobacterium chelonae group