Table 3 Characteristics of NICU patients comparing hypothermia therapy vs. non-hypothermia therapy groups
Variables | Hypothermia therapy (n = 21) | Non-hypothermia therapy (n = 68) | P-value |
|---|---|---|---|
Laboratory testing (7 days after intubation) | |||
CRP (mg/l), median (IQR) | 57.53 (22.10–79.20) | 58.76 (30.57–92.35) | 0.565 |
PCT (ng/ml), median (IQR) | 0.13 (0.10–0.21) | 0.17 (0.08–0.53) | 0.431 |
ALT (U/l), median (IQR) | 35.43 (33.13–39.61) | 44.50 (30.00–61.75) | 0.889 |
Scr (mmol/l), median (IQR) | 50.00 (38.00–76.00) | 58.50 (43.50–84.00) | 0.214 |
White blood cell count (× 109/l) | 7.60 ± 2.31 | 10.10 ± 3.40 | 0.002 |
Neutrophils (× 109/l) | 6.22 ± 2.19 | 8.34 ± 3.04 | 0.004 |
Lymph (× 109/l) | 0.86 ± 0.48 | 1.13 ± 0.61 | 0.072 |
Platelet (× 109/l) * | 137.52 ± 63.20 | 180.60 ± 79.59 | 0.026 |
Use of sedative and analgesics (cumulative use time > = 3d) | |||
Propofol or propofol medium and long chain fat emulsion | 13 (61.9%) | 49 (72.1%) | 0.376 |
Midazolam | 17 (81.0%) | 46 (67.6%) | 0.258 |
Remifentanil or fentanyl | 18 (85.7%) | 62 (91.2%) | 0.755 |