Table 1 Baseline characteristics of patients with acute hepatitis E infection (n = 74)
From: Acute hepatitis E virus superinfection increases mortality in patients with cirrhosis
| Â | Total | No cirrhosis | Cirrhosis | P |
|---|---|---|---|---|
No | 74 (100%) | 52 (70.3%) | 22 (29.7%) | Â |
Age, year | 56.0 (42.8–68.0) | 55.5 (40.3–68.8) | 56.5 (47.0–68.0) | 0.670 |
Male gender | 50 (67.6%) | 34 (65.4%) | 16 (72.7%) | 0.597 |
Diabetes | 11 (14.9%) | 3 (5.8%) | 8 (36.4%) | 0.001 |
Alcohol > 40 g/day | 20 (27.0%) | 11 (21.2%) | 9 (40.9%) | 0.080 |
Hypertension | 13 (17.6%) | 9 (17.3%) | 4 (18.2%) | 1.000 |
CKD | 2 (2.7%) | 2 (3.8%) | 0 (0%) | 1.000 |
Malignancy | 12 (16.2%) | 9 (17.3%) | 3 (13.6%) | 1.000 |
Clinical symptoms | ||||
 Jaundice | 33 (44.6%) | 20 (38.5%) | 13 (59.1%) | 0.128 |
 Fatigue | 18 (24.3%) | 13 (25.0%) | 5 (22.7%) | 0.543 |
 Nausea/vomiting | 10 (13.5%) | 10 (19.2%) | 0 (0%) | 0.028 |
 Fever | 14 (18.9%) | 13 (25.0%) | 1 (4.5%) | 0.052 |
 Abdominal pain | 16 (21.6%) | 12 (23.1%) | 4 (18.2%) | 0.764 |
 No symptom | 14 (18.9%) | 10 (19.2%) | 4 (18.2%) | 1.000 |
 Undercooked meat | 14 (18.9%) | 10 (19.2%) | 4 (18.2%) | 1.000 |
Laboratory data | ||||
 WBC, × 109/L | 6.1 (5.1–9.6) | 6.0 (4.9–9.5) | 6.3 (5.1–10.9) | 0.736 |
 Hemoglobin, g/dL | 13.4 (11.7–14.8) | 13.6 (12.0–15.2) | 13.0 (11.1–14.4) | 0.274 |
 Platelet, × 109/L | 177.5 (116.5–266.3) | 206.5 (142.0–276.8) | 117.0 (83.3–159.8) | < 0.001 |
 AST, U/L | 257.0 (72.5–868.3) | 329.0 (109.5–852.0) | 168.5 (55.0–1288.0) | 0.232 |
 ALT, U/L | 347.5 (89.3–959.3) | 395.5 (129.5–1032.8) | 90.0 (24.5–585.0) | 0.009 |
 Creatinine, mg/dL | 0.82 (0.65–0.91) | 0.80 (0.65–0.89) | 0.84 (0.65–0.93) | 0.452 |
 Bilirubin, mg/dL | 4.3 (1.3–8.7) | 2.2 (0.9–8.2) | 6.8 (2.5–15.7) | 0.008 |
 Albumin, g/dL | 3.7 (3.4–4.1) | 3.9 (3.5–4.2) | 3.5 (2.8–3.8) | 0.003 |
 Sodium, mmol/L | 136.9 (134.4–139.5) | 138.0 (135.0–139.8) | 134.1 (131.4–137.3) | 0.004 |
 PT-INR | 1.13 (1.00–1.44) | 1.06 (0.99–1.16) | 1.51 (1.19–2.02) | < 0.001 |