Seroprevalence of mucosal and cutaneous human papillomavirus (HPV) types among children and adolescents in the general population in Germany

Table 2 Factors associated with seropositivity for HPV-16, HPV seroprevalence study (n = 12,257, sera collected 2003–2006) (results from regression analysis)

	Crude PR (95% CI)	p-value	Fully adjusted PR (95% CI)^a	p-value
Gender			ns^b
Female	Ref
Male	1.1 (0.8–1.4)	0.706
Age group (years)
1–3	Ref		Ref
4–6	1.5 (0.8–3.0)	0.196	1.5 (0.8–3.0)	0.198
7–9	1.6 (0.8–3.3)	0.158	1.6 (0.8–3.2)	0.167
10–11	1.6 (0.8–3.2)	0.184	1.6 (0.8–3.1)	0.195
12–13	1.4 (0.7–2.8)	0.331	1.4 (0.7–2.8)	0.348
14–15	2.0 (1.1–3.7)	0.018	2.1 (1.2–3.7)	0.015
16–17	3.0 (1.6–5.5)	0.001	3.0 (1.6–5.6)	0.001
Region of residence
West Germany	Ref		Ref
East Germany	0.7 (0.5–1.0)	0.055	0.7 (0.5–1.0)	0.025
Urbanity			ns^b
Rural	Ref
Small city	0.8 (0.6–1.3)	0.423
Medium sized city	0.9 (0.6–1.3)	0.499
Large city	0.8 (0.5–1.3)	0.370
Socioeconomic status of parents			ns^b
Low	Ref
Middle	0.8 (0.6–1.1)	0.132
High	0.8 (0.5–1.1)	0.134
Migratory background of parents			ns^b
None	Ref
One parent	0.9 (0.5–1.5)	0.596
Both parents	1.3 (1.0–1.9)	0.077
Number of household members	1.0 (0.9–1.1)	0.752	ns^b
Number of siblings in household	0.9 (0.8–1.1)	0.225
Body Mass Index (BMI)	1.0 (1.0–1.1)	< 0.001	ns^b

PR prevalence ratio, CI confidence interval, Ref reference
^aMutually adjusted for all other variables in the model
^bns = variables were not significantly associated with HPV seroprevalence in the final model and therefore excluded

ISSN: 1471-2334