Table 2 Univariate logistic regression analysis reporting odds ratios, 95% confidence intervals and p values of factors possibly associated with risk of receiving off-label antiretroviral therapy
Children receiving off-label cART (n/N) | % | OR | 95% IC | p-value | |
|---|---|---|---|---|---|
Age at last check | |||||
< 2 years | 3/10 | 30.0% | 1 | ||
≥ 2 years | 47/215 | 21.9% | 1.53 | (0.38–6.15) | 0.548 |
Sex | |||||
Males | 23/104 | 22.1% | 1 | ||
Females | 27/121 | 22.3% | 0.988 | (0.52–1.85) | 0.971 |
Origin | |||||
Foreign Country | 15/91 | 16.5% | 1 | ||
Italy | 35/134 | 26.1% | 1.791 | (0.91–3.51) | 0.090 |
Age at the Beginning of the current regimen | |||||
≥ 2 years | 34/188 | 18.1% | 1 | ||
< 2 years | 16/37 | 43.2% | 3.24 | (1.63–7.30) | 0.001 |
Nr. of previous cART regimens | |||||
< 1 | 15/45 | 33.3% | 1 | ||
1 | 35/180 | 19.4% | 207 | (1.0006–4.26) | 0.048 |
Pre-cART VL* | |||||
Undetectable | 13/81 | 16.0% | 1 | ||
Detectable | 24/76 | 31.6% | 2.414 | (1.13–5.19) | 0.024 |
Missing | 13/68 | 19.1% | 1.236 | (0.53–2.88) | 0.623 |
VL* at last check | |||||
Undetectable | 40/185 | 21.6% | 1 | ||
Detectable | 10/39 | 25.6% | 1.25 | (0.56–2.78) | 0.584 |
Missing | 0/1 | 0.0% | omitted | ||
Pre-cART CD4+ lymphocytes count | |||||
< 15 | 2/14 | 14.3% | 1 | ||
> 15 | 31/137 | 22.6% | 1.755 | (0.37–8.26) | 0.477 |
Missing | 17/74 | 23.0% | 1.789 | (0.36–8.79) | 0.474 |
CD4+ lymphocytes percentage at last check | |||||
< 15% | 4/8 | 50.0% | 1 | ||
> 15% | 46/217 | 21.2% | 0.269 | (0.06–1.12) | 0.071 |