Table 3 Comparisons of discriminating abilities of tested biomarkers presented as areas under the curve (95% CI)
Tested biomarker | AUC (95% CI) | p value | Cut-off value | Sensitivity, (%) | Specificity, (%) |
|---|---|---|---|---|---|
Presepsin | |||||
Sepsis vs. non-infectious organ failure | 0.877 (0.841–0.906) | < 0.001 | 582 (pg/mL) | 70.1 | 89.4 |
Septic shock vs. sepsis | 0.618 (0.558–0.675) | < 0.001 | 1285 (pg/mL) | 50.4 | 76.6 |
Procalcitonin | |||||
Sepsis vs. non-infectious organ failure | 0.908 (0.877–0.934) | < 0.001 | 0.51 (ng/mL) | 75.5 | 93.0 |
Septic shock vs. sepsis | 0.678 (0.619–0.732) | < 0.001 | 2.81 (ng/mL) | 59.1 | 70.9 |
CRP | |||||
Sepsis vs. non-infectious organ failure | 0.858 (0.821–0.890) | < 0.001 | 3.53 (mg/L) | 77.0 | 85.2 |
Septic shock vs. sepsis | 0.559 (0.498–0.618) | 0.088 | 6.62 (mg/L) | 65.7 | 46.8 |