Table 1 Demographic and baseline clinical characteristics of Group B Streptococcus infective endocarditis cases and matched controls
Cases (N = 28) | Controls (N = 84) | (Pearson 2-sided Chi-square, or 2-tailed t test) | |
|---|---|---|---|
Age in years (mean ± SD) | 59.0 ± 16.8 | 65.4 ± 15.5 | P = 0.066 |
Females | 14 (50.0%) | 37 (44.0%) | P = 0.58 |
Non-valvular cardiac disease | 11 (39.3%) | 34 (40.5%) | P = 0.84 |
Atrial fibrillation | 4 (14.3%) | 17 (20.2%) | P = 0.49 |
Coronary artery disease | 9 (32.1%) | 21 (25.0%) | P = 0.46 |
Congestive heart failure | 2 (7.1%) | 8 (9.5%) | P = 0.70 |
Valvular disease | 10 (35.7%) | 7 (8.3%) | P < 0.001 |
Cardiac device | 0 | 4 (4.8%) | P = 0.24 |
Prosthetic valve | 5 (17.9%) | 2 (2.4%) | P = 0.003 |
Diabetes | 12 (42.9%) | 43 (51.2%) | P = 0.48 |
Active malignancy | 3 (10.7%) | 8 (9.5%) | P = 0.86 |
Immunocompromised* | 3 (10.7%) | 12 (14.3%) | P = 0.68 |
Pregnant | 1 (3.6%) | 1 (1.2%) | P = 0.41 |
Post-partum | 0 | 3 (3.6%) | P = 0.31 |
Cirrhosis | 3 (10.7%) | 6 (7.1%) | P = 0.55 |
Genitourinary disease | 4 (14.3%) | 16 (19.0%) | P = 0.57 |
Chronic kidney disease | 6 (21.4%) | 16 (19.0%) | P = 0.78 |
Hemodialysis | 1 (3.6%) | 5 (6.0%) | P = 0.63 |
Injection drug use | 7 (25.0%) | 2 (2.4%) | P < 0.001 |
Alcohol use disorder | 4 (14.3%) | 1 (1.2%) | P = 0.004 |