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Table 2 Risk factors for stroke by logistic regression analysis models among HAART-naive people living with HIV (PLWH)

From: Stroke among highly active antiretroviral therapy-naive people living with the human immunodeficiency virus in China: a retrospective study of the characteristics, risk factors, and prognosis

Variables

Unadjusted

Adjusted

OR (95% CI)

p

OR (95% CI)

p

Age < 30 years

1

 

1

 

30 ≤ Age < 55 years

2.165 (1.163–4.033)

0.015

1.903 (1.005–3.603)

0.048

Age ≥ 55 years

6.176 (3.096–12.321)

 < 0.001

4.104 (1.928–8.737)

 < 0.001

Gender-Male

0.922 (0.488–1.744)

0.803

–

–

Cigarette smoking history

1.628 (1.096–2.419)

0.016

1.339 (0.882–2.032)

0.170

Alcoholic drinking history

1.147 (0.748–1.759)

0.530

–

–

Laboratory results

 CD4 < 200 cells/µL

1.993 (1.031–3.853)

0.040

2.005 (1.008–3.985)

0.047

 TC > 6.2 mmol/L

0.795 (0.108–5.870)

0.822

–

–

 TG > 2.3 mmol/L

1.244 (0.700–2.211)

0.457

–

–

 HDL < 0.96 mmol/L

1.468 (0.779–2.766)

0.235

–

–

Complications

 Diabetes

5.103 (2.884–9.028)

 < 0.001

3.268 (1.744–6.125)

 < 0.001

 Hpertension

3.523 (2.295–5.406)

 < 0.001

2.301 (1.425–3.717)

0.001

 Syphilis

2.084 (1.378–3.152)

0.001

2.003 (1.300–3.089)

0.002

 Severe pneumonia

1.705 (0.972–2.990)

0.063

1.354 (0.744–2.462)

0.321

 AIDS-defining CNS diseases

6.875 (4.001–11.812)

 < 0.001

7.719 (4.348–13.703)

 < 0.001

Opportunistic infections

 CMV

1.192 (0.783–1.815)

0.413

–

–

 PCP

1.095 (0.733–1.635)

0.659

–

–

 TB

0.637 (0.385–1.054)

0.079

0.636 (0.376–1.077)

0.092

 Cryptococcosis

1.204 (0.576–2.517)

0.621

–

–

  1. HDL high-density lipoprotein; LDL low-density lipoprotein; TC total cholesterol; TG triglyceride; CMV cytomegalovirus; TB tuberculosis; PCP pneumocystis pneumonia; CNS central nervous system; OR odds ratio