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Table 3 Risk factors associated with 28 day and 90 day mortality by a Multivariate COX’s Hazard Model in HVI and NVI groups

From: Hepatitis B-related acute-on-chronic liver failure induced by hepatotropic viral insult is associated with worse prognosis than that induced by non-virus insult

 

28 day mortality

90 day mortality

Variables

Hazard ratio

95%CI

P Value

Hazard ratio

95%CI

P value

HVI (n = 82)

 ACLF Type

0.231

0.061–0.870

0.030

1.283

0.722–2.279

0.395

 Age

1.053

0.989–1.122

0.107

1.073

1.024–1.125

0.003

 TB

1.004

1.001–1.007

0.020

1.002

0.999–1.004

0.129

 PTA

0.934

0.878–0.993

0.029

0.943

0.900–0.988

0.013

 Creatinine

1.002

0.998–1.007

0.349

1.005

1.002–1.008

0.003

 Na

1.049

0.951–1.157

0.335

0.977

0.920–1.138

0.457

 WBC

0.781

0.887–1.173

0.781

1.000

0.889–1.125

0.999

 Neut

1.003

0.951–1.059

0.903

0.986

0.948–1.126

0.497

NVI (n = 121)

 ACLF Type

0.506

0.142–1.802

0.293

0.386

0.134–1.113

0.078

 Age

1.028

0.985–1.073

0.208

1.014

0.980–1.050

0.426

 TB

1.003

0.999–1.006

0.110

1.003

1.000–1.005

0.053

 PTA

0.952

0.897–1.010

0.100

0.968

0.928–1.010

0.128

 Creatinine

1.007

0.992–1.021

0.368

1.011

0.999–1.023

0.062

 Na

1.016

0.929–1.021

0.722

1.009

0.943–1.079

0.804

 WBC

1.010

0.935–1.090

0.802

0.996

0.934–1.062

0.904

 Neut

1.034

0.977–1.094

0.249

1.039

0.996–1.084

0.074

  1. HVI hepatotropic viral insult, NVI non-virus insult, TB total bilirubin, PTA prothrombin activity, Na serum sodium, WBC white blood cell, NEUT neutrophils