Clinical characteristics of Gram-negative and Gram-positive bacterial infection in acute cholangitis: a retrospective observational study

Table 3 Differences in organ function and outcomes of cholangitis patients with different culture results

	No growth	With bacterial growth
Variables	No growth	Total	P-value^c	Gram-negative	Gram-positive	Gram-negative + Gram-positive	P-value^d
Variables	(n = 111)	(n = 313)		(n = 155)	(n = 48)	(n = 110)	P-value^d
Septic shock, n (%)	3 (27.0)	70 (22.4)	< 0.001	26 (16.8)	9 (18.8)	35 (31.8)^a	0.012
Neurological dysfunction, n (%)	4 (3.6)	55 (17.6)	< 0.001	15 (9.7)	8 (16.7)	32 (29.1)^a	< 0.001
Hepatic dysfunction, n (%)	4 (3.6)	41 (13.1)	0.005	13 (8.4)	3 (6.3)	25 (22.7)^a,b	0.001
Hematological dysfunction, n (%)	10 (9.0)	96 (30.7)	< 0.001	39 (25.2)	15 (31.3)	42 (38.2)	0.077
Renal dysfunction, n (%)	4 (3.6)	44 (14.1)	0.003	20 (12.9)	8 (16.7)	16 (14.5)	0.793
Respiratory dysfunction, n (%)	2 (1.8)	65 (20.8)	< 0.001	21 (13.5)	8 (16.7)	36 (32.7)^a	0.001
Intensive care unit admission (day)	0.00 (0.00–0.00)	0.00 (0.00–2.00)	< 0.001	0.00 (0.00–1.00)	0.00 (0.00–2.00)	0.00 (0.00–3.00)^a	0.032
Hospital stay (day)	15.00 (11.00–19.00)	17.00 (12.50–24.00)	< 0.001	16.00 (12.00–22.00)	16.50 (12.00–20.75)	21.00 (15.00–26.00)^a,b	0.002
Death, n (%)	0 (0)	26 (8.3)	0.002	4 (2.6)	2 (4.2)	20 (18.2)^a	< 0.001

^a,bUsed to represent the pairwise comparison results between the Gram-negative group, Gram-positive group and Gram-negative + Gram-positive group. ^athere is a difference compared with the Gram-negative group; ^bthere is a difference compared with the Gram-positive group; (p < 0.05)
P-Value^c: comparison results between the No growth group and the With bacterial growth group. P-Value^d: comparison results between the Gram-negative group, Gram-positive group and Gram-negative + Gram-positive group

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