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Table 1 Demographic characteristics of the bacterial and viral groups

From: C-reactive protein velocity discriminates between acute viral and bacterial infections in patients who present with relatively low CRP concentrations

Table of characteristics

Name

Viral

N = 62

Bacterial

N = 74

AUC

CI

MW

p value

ChiSquare

p value

Age (years)

66.6 ± 18.4

80.2 ± 13.7

0.74

–

< 0.001

–

Women (%)

58.1%

43.2%

0.57

–

–

0.12

Δt Antibiotic (h)

5.4 ± 5

4.2 ± 4.2

0.58

–

0.097

–

eCRP

2.9 ± 0.3

2.8 ± 0.2

0.58

–

0.116

–

CRP1 (mg/L)

16.2 ± 8.6

14.8 ± 8.5

0.55

0.46–0.62

0.336

–

Δt onset of symptoms to CRP1 (h)

72.7 ± 104

29.1 ± 60.8

0.75

0.67–0.82

< 0.001

–

eCRPv (mg/L/h)

0.8 ± 1.6

1.2 ± 1.1

0.7

0.62–0.77

0.001

–

CRP2 (mg/L)

30.2 ± 21.9

75.6 ± 51.3

0.77

0.70–0.84

< 0.001

–

Δt CRP1 to CRP2 (h)

14.9 ± 5.9

13.1 ± 6.4

0.58

–

0.108

–

CRPv (mg/L/h)

0.9 ± 1.2

4.4 ± 2.7

0.86

0.79–0.91

< 0.001

–

  1. Values are mean ± SD, % for women, MW p-value of the Mann–Whitney test, Chi2p value for the Pearson’s Chi-squared test. In the AUC computation, the positive class was bacterial infection for these parameters—eCRPv, CRP2, CRPv and viral infection for these parameters—CRP1, Δt onset of symptoms to CRP1, Δt CRP1 to CRP2. CRP1 and CRP2: the first and second CRP consecutive measurements after admission. Δt Antibiotic: the time difference between CRP1 and antibiotic administration time. eCRP: estimated CRP is the average CRP concentration in the healthy population compatible by age and sex. Δt Symptoms onset to CRP1: the time difference between onset of symptoms and CRP1. eCRPv: the difference eCRP and CRP1 divided by Δt onset of symptoms to CRP1. CRPv: the difference between CRP1 and CRP2 divided by the time difference between the tests
  2. AUC Area under the curve, CRP C-reactive protein, CRPv C-reactive protein velocity, eCRPv Estimated C-reactive protein velocity
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BMC Infectious Diseases

ISSN: 1471-2334

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