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Table 2 Characteristics of children presenting with IPD from different regions of China

From: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

 

All Patients

n = 806

North

n = 368

East

n = 161

South

n = 237

Northwest

n = 40

p*

Median age, years (interquartile range)

1.3 (0.8–3.1)

1.3 (0.7–3.2)

1.6 (0.8–3.5)

1.3 (0.8–2.9)

1.1 (0.7–3.0)

0.287

Male

491 (60.9)

217 (59.0)

113 (70.2)

139 (58.6)

22 (55.0)

0.058

Underlying disease

101 (12.5)

59 (16.0)

25 (15.5)

14 (5.9)

3 (7.5)

0.001

ICU admission

241 (29.9)

124 (33.7)

41 (25.5)

63 (26.6)

13 (32.5)

0.144

Tracheal intubation

112 (13.9)

71 (19.3)

20 (12.4)

17 (7.2)

4 (10.0)

0.000

Death

92 (11.4)

54 (14.7)

18 (11.2)

16 (6.8)

4 (10.0)

0.023

Meningitis

314 (39.0)

145 (39.4)

61 (37.9)

90 (38.0)

18 (45.0)

0.845

Spn not susceptible to penicillin

431 (53.5)

212 (57.6)

64 (39.8)

135(57.0)

20 (50.0)

0.001

Spn not susceptible to cefotaxime

237 (29.4)

127 (34.5)

34 (21.1)

61 (25.7)

15 (37.5)

0.005

  1. Spn Streptococcus pneumoniae
  2. *All the four regions were compared