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Table 2 Characteristics of children presenting with IPD from different regions of China

From: Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study

  All Patients
n = 806
North
n = 368
East
n = 161
South
n = 237
Northwest
n = 40
p*
Median age, years (interquartile range) 1.3 (0.8–3.1) 1.3 (0.7–3.2) 1.6 (0.8–3.5) 1.3 (0.8–2.9) 1.1 (0.7–3.0) 0.287
Male 491 (60.9) 217 (59.0) 113 (70.2) 139 (58.6) 22 (55.0) 0.058
Underlying disease 101 (12.5) 59 (16.0) 25 (15.5) 14 (5.9) 3 (7.5) 0.001
ICU admission 241 (29.9) 124 (33.7) 41 (25.5) 63 (26.6) 13 (32.5) 0.144
Tracheal intubation 112 (13.9) 71 (19.3) 20 (12.4) 17 (7.2) 4 (10.0) 0.000
Death 92 (11.4) 54 (14.7) 18 (11.2) 16 (6.8) 4 (10.0) 0.023
Meningitis 314 (39.0) 145 (39.4) 61 (37.9) 90 (38.0) 18 (45.0) 0.845
Spn not susceptible to penicillin 431 (53.5) 212 (57.6) 64 (39.8) 135(57.0) 20 (50.0) 0.001
Spn not susceptible to cefotaxime 237 (29.4) 127 (34.5) 34 (21.1) 61 (25.7) 15 (37.5) 0.005
  1. Spn Streptococcus pneumoniae
  2. *All the four regions were compared