Table 3 CSF analysis characteristics of HIV-infected patients with C. neoformans versus C. curvatus/C. laurentii meningitis
Variable | Cryptococcal species | p | |
|---|---|---|---|
C. neoformans na (%)b | C. curvatus/C. laurentii na (%)b | ||
The clear appearance of CSF | 20 (87.0) | 6 (100) | 1 |
Mean opening pressure (cm of water) | 30.0 ± 7.6 | 28.3 ± 7.6 | 1 |
CSF opening pressure cm of water) | 1 | ||
Normal (< 20) | 1 (12.5) | 0 | |
High (20–30) | 1 (12.5) | 1 (33.3) | |
Very high (≥ 30) | 6 (75.0) | 4 (66.6) | |
Glycorrachia (mg/dL) ± SD | 46.7 ± 11.2 | 66.1 ± 22.5 | 0.04 |
Glycorrachia (mg/dL) | 0.01 | ||
Low (≤ 50) | 9 (90.0) | 1 (20.0) | |
Normal (50–60) | 0 | 1 (20.0) | |
High (≥ 60) | 1 (10.0) | 3 (60.0) | |
Positive pandy | 7 (43.8) | 3 (60.0) | 0.63 |
Cytorrachia (cells/mm3) ± SD | 41.52 ± 51.6 | 15.8 ± 23.5 | 0.25 |
Lymphocytic cytorrachia | 5 (33.3) | 1 (50.0) | 1 |
Positive culture on CSF | 23 (100) | 6 (100) | 1 |
Positive India ink on CSF | 18 (78.3) | 2 (33.3) | 0.06 |
CrAg present on CSF | 22 (95.7) | 4 (66.7) | 0.09 |