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Table 1 Demographic and clinical characteristics of HIV-infected patients with C. neoformans versus C. curvatus/C. laurentii meningitis

From: Comparison of clinical and biological characteristics of HIV-infected patients presenting Cryptococcus neoformans versus C. curvatus/C. laurentii meningitis

Variable Cryptococcal species p
C. neoformans
na (%)b
C. curvatus/C. laurentii
na (%)b
Demographic characteristics
 Age, mean (year) ± SD 36.7 ± 11·3 38.3 ± 9.1 0.1
 Female sex 15 (65.2) 4 (66.7) 1
 Marital status 0.56
  Single 8 (34.8) 3(60.0)  
  Married/free union 10 (43.5) 2 (40.0)  
  Divorced/separated/widowed 5 (21.7) 0  
 Clinical stage of HIV (WHO) 0.19
  Stage III 0 1 (20.0)  
  Stage IV 21 (100) 4 (80.0)  
  Antiretroviral therapy (ART) 20 (87.0) 3 (50.0) 0.08
 Clinical signs
  Headache 23 (100) 3 (50.0) 0.005
  Fever 18 (78.0) 2 (33.3) 0.05
  Weight loss 16 (69.6) 2 (33.3) 0.16
  Disorder of consciousness 11 (47.8) 0 0.05
  Meningeal signs 7 (30.4) 0 0.28
  Memory impairment 6 (26.1) 0 0.29
  Convulsions 4 (17.4) 0 0.55
  Dizziness 4 (17.4) 1 (16.7) 1
  Visual disturbances 0 2 (33.3) 0.03
  Hemiplegia 0 1 (16.7) 0.2
  Neck pain 1 (4.3) 0 1
  Facial paralysis 0 1 (16.7) 0.2
Mean temperature (°C) ± SD 36.8 ± 0.8 36.1 ± 1.3 0.08
Duration of symptoms 18.3 ± 14.7 19.3 ± 9.4 0.8
  1. aWith available data
  2. bPercentage of columns calculated for each group