Neonatal sepsis in Sana’a city, Yemen: a predominance of Burkholderia cepacia

BMC Infectious Diseases

Table 3 Association of clinical manifestations and hematological factors with culture-confirmed sepsis among septic neonates admitted to referral hospitals in Sana’a city, Yemen, in the period from January 15 to March 30, 2020 (N = 199)

Variable	N	Culture-confirmed neonatal sepsis
Variable	N	n (%)	Chi-square value	p value
Clinical manifestations
Poor feeding
No	79	58 (73.4)	1.18	0.277
Yes	120	96 (80.0)
Convulsion^a
No	182	137(75.3)		0.015
Yes	17	17 (100)
Irritability^a
No	164	124(75.6)		0.266
Yes	35	30 (85.7)
Jaundice
No	141	107(75.9)	0.62	0.430
Yes	58	47 (81.0)
Lethargy
No	70	52 (74.3)	0.59	0.411
Yes	129	102(79.1)
Respiratory rate^a
Normal	53	40 (75.5)		0.96
Tachypnea	135	105 (77.8)
Apnea	11	9 (81.8)
Temperature^a
Normal	154	115 (74.7)		0.045
Hyperthermia	36	33 (91.7)
Hypothermia	9	6 (66.7)
Hematological factors
C-reactive protein
Non-reactive < 6 ml/dl	74	48 (64.9)	11.3	0.001
Reactive	113	97 (85.8)
WBC^a
Normal	65	49 (75.4)		0.891
High	126	99 (78.6)
Low	6	5 (83.3)
Platelets^a
Normal	124	91 (73.4)		0.158
High	5	5 (100)
Low	68	57 (83.8)

N, number of suspected neonates; n, number of culture-confirmed septic neonates; normal WBC 4000–10,000/mm³; normal platelets 150,000–450,000; normal respiratory rate, 30–50permint
^aFisher’s exact test was used

ISSN: 1471-2334