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Table 2 Frequency of plasma leakage or dengue haemorrhagic fever (DHF) reported among laboratory confirmed dengue patients in included studies

From: Plasma leakage in dengue: a systematic review of prospective observational studies

Study Plasma leakage DHF
as % of symptomatic and asymptomatic patients (n/N) as % of symptomatic patients (n/N)* as % of symptomatic and hospitalised patients (n/N)** as % of symptomatic and asymptomatic patients (n/N) as % of symptomatic patients (n/N)* as % of symptomatic and hospitalised patients (n/N)**
Adil 2020 [8] 38.33 (69/180) 41.11 (74/180)
Alexander 2011 [9]   50.12 (786/1568) 50.35 (715/1420)
Avirutnan 2006 [11]   69.94 (114/163)
Basuki 2010 [12] 27.59 (40/145) 51.72 (75/145)
Biswas 2015 [13]   24.97 (197/789) 28.68 (195/680)
Bodinayaka 2018 [14] 2.32 (9/388)  
Capeding 2015 [15]   83.67 (1496/1788)
Chattergee 2017 [16]   26.03 (57/209)
Cordeiro 2007 [17]   10.03 (29/289)
Fariz-Safhan 2014 [18] 62.5 (90/144) 59.72 (86/144)
Guilarde 2008 [19]   23.24 (43/185) 44.32 (39/88)
Herath 2019 [20] 37.43 (67/179)  
Jagadishkumar 2012 [21]   46.36 (51/110)
Jain 2017 [22]   46.34 (171/369)
Kirawittaya 2015 [23]   34.25 (62/181)
Kittigul 2007 [24]   94.76 (271/286)
Kularatnam 2019 [25]   23.08 (30/130)
Kulasinghe 2016 [26] 52.53 (83/158)  
Laul 2016 [27]   19.09 (21/110)
Malavige 2006 [29]   82.69 (86/104)
Malavige 2006 [30]   69.44 (75/108)
Manamperi 2019 [31]   48.41 (76/157)
Pham 2009 [32] 33.77 (51/151)  
Phuong 2004 [33]   50.55 (319/631)
Poeranto 2016 [34]##   21.36 (47/220)
Potts 2010 [47]   37.46 (236/630)
Prasad 2020 [35] 38.24 (39/102)  
Premaratne 2013 [36] 40.2 (41/102)  
Raman 2013 [37]   44.0 (88/200) 75.86 (88/116)
Seet 2006 [39]   19.69 (25/127)
Senaratne 2016 [40]   19.20 (43/224)
Sigera 2021 [49] 46.95 (200/426)  
Suwarto 2016 [41] 58.72 (101/172)  
Tang 2008 [48]   0 (0/353)
Taylor 2015 [42] 23.26 (30/129)  
Thomas 2012[43] 14.27 (102/715) 7.41 (53/715)
Trung 2012 [50] 46.43 (611/1316)  
Vasanwala 2014 [44]   20.24 (34/168)
Yacoub 2017 [45] 51.43 (126/245) 70.32 (109/155)  
Yung 2015 [46]   17.48 (82/469) 38.14 (82/215)
Anderson 2011 [10]   6.33 (36/569) 14.23 (36/253) 72.0 (36/50)
L’Azou 2016 [28]   4.24 (30/708) 28.85 (30/104)
Sabchareon 2012 [38]   10.66 (42/394) 21.76 (42/193)
Total NC 36.79 (1642/4462) NC 28.56 (1304/4566) 45.68 (4758/10417)
  1. *Includes patients that were managed as in- or out-patients, **includes patients that were managed as in-patients only, NC Not calculated