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Table 2 Frequency of plasma leakage or dengue haemorrhagic fever (DHF) reported among laboratory confirmed dengue patients in included studies

From: Plasma leakage in dengue: a systematic review of prospective observational studies

Study

Plasma leakage

DHF

as % of symptomatic and asymptomatic patients (n/N)

as % of symptomatic patients (n/N)*

as % of symptomatic and hospitalised patients (n/N)**

as % of symptomatic and asymptomatic patients (n/N)

as % of symptomatic patients (n/N)*

as % of symptomatic and hospitalised patients (n/N)**

Adil 2020 [8]

38.33 (69/180)

41.11 (74/180)

Alexander 2011 [9]

 

50.12 (786/1568)

50.35 (715/1420)

Avirutnan 2006 [11]

 

69.94 (114/163)

Basuki 2010 [12]

27.59 (40/145)

51.72 (75/145)

Biswas 2015 [13]

 

24.97 (197/789)

28.68 (195/680)

Bodinayaka 2018 [14]

2.32 (9/388)

 

Capeding 2015 [15]

 

83.67 (1496/1788)

Chattergee 2017 [16]

 

26.03 (57/209)

Cordeiro 2007 [17]

 

10.03 (29/289)

Fariz-Safhan 2014 [18]

62.5 (90/144)

59.72 (86/144)

Guilarde 2008 [19]

 

23.24 (43/185)

44.32 (39/88)

Herath 2019 [20]

37.43 (67/179)

 

Jagadishkumar 2012 [21]

 

46.36 (51/110)

Jain 2017 [22]

 

46.34 (171/369)

Kirawittaya 2015 [23]

 

34.25 (62/181)

Kittigul 2007 [24]

 

94.76 (271/286)

Kularatnam 2019 [25]

 

23.08 (30/130)

Kulasinghe 2016 [26]

52.53 (83/158)

 

Laul 2016 [27]

 

19.09 (21/110)

Malavige 2006 [29]

 

82.69 (86/104)

Malavige 2006 [30]

 

69.44 (75/108)

Manamperi 2019 [31]

 

48.41 (76/157)

Pham 2009 [32]

33.77 (51/151)

 

Phuong 2004 [33]

 

50.55 (319/631)

Poeranto 2016 [34]##

 

21.36 (47/220)

Potts 2010 [47]

 

37.46 (236/630)

Prasad 2020 [35]

38.24 (39/102)

 

Premaratne 2013 [36]

40.2 (41/102)

 

Raman 2013 [37]

 

44.0 (88/200)

75.86 (88/116)

Seet 2006 [39]

 

19.69 (25/127)

Senaratne 2016 [40]

 

19.20 (43/224)

Sigera 2021 [49]

46.95 (200/426)

 

Suwarto 2016 [41]

58.72 (101/172)

 

Tang 2008 [48]

 

0 (0/353)

Taylor 2015 [42]

23.26 (30/129)

 

Thomas 2012[43]

14.27 (102/715)

7.41 (53/715)

Trung 2012 [50]

46.43 (611/1316)

 

Vasanwala 2014 [44]

 

20.24 (34/168)

Yacoub 2017 [45]

51.43 (126/245)

70.32 (109/155)

 

Yung 2015 [46]

 

17.48 (82/469)

38.14 (82/215)

Anderson 2011 [10]

 

6.33 (36/569)

14.23 (36/253)

72.0 (36/50)

L’Azou 2016 [28]

 

4.24 (30/708)

28.85 (30/104)

Sabchareon 2012 [38]

 

10.66 (42/394)

21.76 (42/193)

Total

NC

36.79 (1642/4462)

NC

28.56 (1304/4566)

45.68 (4758/10417)

  1. *Includes patients that were managed as in- or out-patients, **includes patients that were managed as in-patients only, NC Not calculated