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Table 1 Human Infections with Mycobacterium marseillesnse

From: Tenosynovitis caused by Mycobacterium marseillense, initially identified as Mycobacterium avium complex using AccuProbe and COBAS TaqMan

No. Age Sex Country Immunocompromising condition Site of infection Identification methods Antibiotics therapy Duration of therapy Outcome References
1 56 M China Systemic lupus
erythematosus
Pneumonia Gene Sequencing (16 S rRNA, ITS,hsp65) Nonea Not documented unknown [6]
2 65 M Italy None Pneumonia Gene Sequencing (rpoB, ITS),
Genotype CM/AS (misidentified as MIN)
1. RFP, INH, AMK
2. LVFX, TRD, AZM
3. EB, RFP, AZM
54 monthsb Cured [7]
3 4 F Italy None Lymphadenitis Gene Sequencing (ITS), Genotype CM CAM, RFP + EBc 6 months Cured [8]
4 59 F China None Skin infection of face Gene Sequencing
(16 S rRNA, hsp65, rpoB)
1. RFP, INH, EB, PZA
2. CAM, RFP, EB
3. CAM, MFLX, AMK
15 monthsd Cured [9]
5 73 M US Renal transplant
due to polycystic
kidney disease
Tenosynovitis of wrist Not documented AZM, EB, Rifabutin 6 months Cured [10]
6 85 M Japan None Tenosynovitis of wrist MALDI TOF-MS,
Gene Sequencing (rpoB, hsp65),
Accuprobe (positive for MAC)
1. CAM, EB, RFP
2. CAM, EB
5 monthse Died from
unrelated cause
This Study
  1. M, male; F, female; RFP, rifampin; INH, isoniazid; AMK, amikacin; LVFX, levofloxacin; TRD, terizidone; AZM, azithromycin; EB, ethambutol; CAM, clarithromycin; MFLX, moxifloxacin
  2. aMacrolide and rifampin was planned but canceled due to an acute intracranial hemorrhage
  3. bRegimen 1 for 12 months, regimen 2 for 36 months, regimen 3 for 6 months
  4. cEthanbutol was later added due to delay of the surgical scar
  5. dRegimen 1 for 10 months, regimen 2 for 3 months, regimen 3 for 2 months
  6. e Regimen 1 for 2 months, regimen 2 for 3 months